Results 21 to 30 of about 162,094 (212)

The frequency of aberrant lymphoid antigens expression in 202 Iraqi patients with de novo acute myeloid leukemia

open access: yesIraqi Journal of Hematology, 2017
Background: Immunophenotyping improves both accuracy and reproducibility of acute leukemia classification and is considered, particularly useful for identifying acute myeloid leukemia (AML) with lymphoid marker expression.
Wafaa Mohammed Al-Anizi   +1 more
doaj   +1 more source

Role of the bone morphogenic protein pathway in developmental haemopoiesis and leukaemogenesis [PDF]

open access: yes, 2016
Myeloid leukaemias share the common characteristics of being stem cell-derived clonal diseases, characterised by excessive proliferation of one or more myeloid lineage.
Toofan, Parto, Wheadon, Helen
core   +1 more source

Biphenotypic Acute Leukemia versus Myeloid Antigen-Positive ALL: Clinical Relevance of WHO Criteria for Mixed Phenotype Acute Leukemia

open access: yesCase Reports in Hematology, 2018
Updated WHO criteria define mixed phenotype acute leukemia (MPAL) with more stringent diagnostic criteria than the formerly described entity biphenotypic acute leukemia (BAL). The changes in diagnostic criteria influence management by assigning weight to
William A. Hammond   +5 more
doaj   +1 more source

Erythematous Macular Eruption in an Older Woman [PDF]

open access: yes, 2019
A white woman in her 70s with advanced Alzheimer disease was referred to the hematology clinic for evaluation of a high hemoglobin level (169 g/L; normal range, 120-160 g/L) and red blood cell count (5.67 × 1012/L; normal range, 3.8-4.8 × 1012/L) as well
Kernohan, Neil   +2 more
core   +2 more sources

Retrovirus-Mediated Expression of E2A-PBX1 Blocks Lymphoid Fate but Permits Retention of Myeloid Potential in Early Hematopoietic Progenitors.

open access: yesPLoS ONE, 2015
The oncogenic transcription factor E2A-PBX1 is expressed consequent to chromosomal translocation 1;19 and is an important oncogenic driver in cases of pre-B-cell acute lymphoblastic leukemia (ALL).
Mark W Woodcroft   +6 more
doaj   +1 more source

Causal pathways in lymphoid leukemia: the gut microbiota, immune cells, and serum metabolites

open access: yesFrontiers in Immunology
BackgroundWe employed Mendelian randomization (MR) to investigate the causal relationship between the gut microbiota and lymphoid leukemia, further exploring the causal relationships among immune cells, lymphoid leukemia, and potential metabolic ...
Xin Zhuang   +8 more
doaj   +1 more source

Clonal Evolution of B-Cell Acute Lymphoblastic Leukemia with del(9)(p13p21) into Mixed Phenotype Acute Leukemia Presenting as an Isolated Testicular Relapse

open access: yesReports, 2019
Lineage switch in acute leukemias is a well-reported occurrence; however, most of these cases involve a switch from either lymphoid to myeloid or myeloid to lymphoid lineage.
Lane H. Miller   +4 more
doaj   +1 more source

Benign TdT-positive cells in pediatric and adult lymph nodes: a potential diagnostic pitfall [PDF]

open access: yes, 2018
Benign TdT-positive cells have been documented in a variety of non-hematopoietic tissues. Scant data are however available on their presence in non-neoplastic lymph nodes.
AGOSTINELLI, CLAUDIO   +8 more
core   +1 more source

Predictive value of proinflammatory activation in prognosis of cardiovascular events after treatment of chronic lymphoid leukemia

open access: yesZaporožskij Medicinskij Žurnal, 2017
Aim: To evaluate the prognostic value of circulating interleukin-6 and CD40 ligand in patients after chronic lymphoid leukemia treatment. Materials and Methods: 193 patients with chronic lymphoid leukemia after chemotherapy were included in the study.
B. B. Samura
doaj   +1 more source

Cytogenetic aberration in mixed-phenotype acute leukemia in children: A single-center retrospective review

open access: yesPediatrics and Neonatology, 2021
Background: Mixed-phenotype acute leukemia (MPAL) poses a diagnostic and therapeutic dilemma. No consensus exists on the strategy to assign patients with MPAL to either lymphoid- or myeloid-directed treatment.
Tsung-Yen Chang   +6 more
doaj   +1 more source

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