Results 31 to 40 of about 162,094 (212)
Nature Communications, 2018 The stromal microenvironment plays a key role in the expansion of chronic lymphocytic leukemia. Here, the authors use the Eµ-TCL1 mouse model to show that leukemic B-cells induce the activation of retinoic acid synthesis in stromal cells of the lymphoid ...
Diego Farinello +27 more
doaj +1 more source
A Tale of Two Hematological Malignancies: CML Followed by CLL in the Same Patient
Annals of Internal Medicine: Clinical Cases, 2023 Studies have reported second malignancies occurring in patients with chronic myeloid leukemia (CML) or chronic lymphoid leukemia (CLL). We discuss the case of a 77-year-old man diagnosed with CLL who later developed CML.
Insija Selene +4 more
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Advances in Hematology, 2020 Introduction. Leukemia is a heterogeneous group of hematological disorder which comprise several diverse and biologically distinct subgroups. Leukemia represents the 11th and 10th most frequent cause of cancer morbidity and mortality worldwide ...
Woldeteklehaymanot Kassahun +5 more
doaj +1 more source
Treatment of Acute Lymphoid Leukemia Refractory to Classic First-Line and Rescue Protocols
International Journal of Hematology-Oncology and Stem Cell Research, 2020 Acute Lymphoblastic Leukemia is a very aggressive malignant disorder of lymphoid cells in adults, with recurrence (30 to 60% of the cases) after the initial treatment.
Flávia Tobaldini Russo +10 more
doaj +1 more source
Emerging targets in human lymphoma: targeting the MYD88 mutation [PDF]
, 2016 B cell neoplasms co-opt the molecular machinery of normal B cells for their survival. Technological advances in cancer genomics has significantly contributed to uncovering the root cause of aggressive lymphomas, revealing a previously unknown link ...
Horikawa, Keisuke +2 more
core +1 more source
Frontiers in OncologyBackgroundLymphocytic leukemia (LL) is a prominent group of hematological cancers afflicting both children and adults of all backgrounds and demographics.
Shannon Blee +5 more
doaj +1 more source
Possible role of GADD45γ methylation in diffuse large B-cell Lymphoma: Does it affect the progression and tissue involvement? [PDF]
, 2015 Objective: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma among adults and is characterized by heterogeneous clinical, immunophenotypic, and genetic features.
Barış, İkbal Cansu +10 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu +20 more
wiley +1 more source
Long Non-Coding RNA Signatures in Lymphopoiesis and Lymphoid Malignancies
Non-Coding RNA, 2023 Lymphoid cells play a critical role in the immune system, which includes three subgroups of T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in lymphopoiesis has revolutionized our understanding of the regulatory ...
Hamed Baghdadi +8 more
doaj +1 more source
Invariant NKT cells contribute to chronic lymphocytic leukemia surveillance and prognosis [PDF]
, 2017 Chronic lymphocytic leukemia (CLL) is characterized by the expansion of malignant CD5(+) B lymphocytes in blood, bone marrow and lymphoid organs. CD1d-restricted invariant Natural Killer T (iNKT) cells are innate-like T lymphocytes strongly implicated in
Azzimonti, Laura +17 more
core +1 more source