Results 31 to 40 of about 157,947 (291)

Predictive value of proinflammatory activation in prognosis of cardiovascular events after treatment of chronic lymphoid leukemia

open access: yesZaporožskij Medicinskij Žurnal, 2017
Aim: To evaluate the prognostic value of circulating interleukin-6 and CD40 ligand in patients after chronic lymphoid leukemia treatment. Materials and Methods: 193 patients with chronic lymphoid leukemia after chemotherapy were included in the study.
B. B. Samura
doaj   +1 more source

A Tale of Two Hematological Malignancies: CML Followed by CLL in the Same Patient

open access: yesAnnals of Internal Medicine: Clinical Cases, 2023
Studies have reported second malignancies occurring in patients with chronic myeloid leukemia (CML) or chronic lymphoid leukemia (CLL). We discuss the case of a 77-year-old man diagnosed with CLL who later developed CML.
Insija Selene   +4 more
doaj   +1 more source

A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression

open access: yesNature Communications, 2018
The stromal microenvironment plays a key role in the expansion of chronic lymphocytic leukemia. Here, the authors use the Eµ-TCL1 mouse model to show that leukemic B-cells induce the activation of retinoic acid synthesis in stromal cells of the lymphoid ...
Diego Farinello   +27 more
doaj   +1 more source

Benign TdT-positive cells in pediatric and adult lymph nodes: a potential diagnostic pitfall [PDF]

open access: yes, 2018
Benign TdT-positive cells have been documented in a variety of non-hematopoietic tissues. Scant data are however available on their presence in non-neoplastic lymph nodes.
AGOSTINELLI, CLAUDIO   +8 more
core   +1 more source

Analysis of lymphocytic leukemia trends among gender, race, age, and regional groups in the U.S. between 1999-2022: a CDC-WONDER database study

open access: yesFrontiers in Oncology
BackgroundLymphocytic leukemia (LL) is a prominent group of hematological cancers afflicting both children and adults of all backgrounds and demographics.
Shannon Blee   +5 more
doaj   +1 more source

Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study

open access: yesAdvances in Hematology, 2020
Introduction. Leukemia is a heterogeneous group of hematological disorder which comprise several diverse and biologically distinct subgroups. Leukemia represents the 11th and 10th most frequent cause of cancer morbidity and mortality worldwide ...
Woldeteklehaymanot Kassahun   +5 more
doaj   +1 more source

Treatment of Acute Lymphoid Leukemia Refractory to Classic First-Line and Rescue Protocols

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2020
Acute Lymphoblastic Leukemia is a very aggressive malignant disorder of lymphoid cells in adults, with recurrence (30 to 60% of the cases) after the initial treatment.
Flávia Tobaldini Russo   +10 more
doaj   +1 more source

Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]

open access: yes, 2016
Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht   +13 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Long Non-Coding RNA Signatures in Lymphopoiesis and Lymphoid Malignancies

open access: yesNon-Coding RNA, 2023
Lymphoid cells play a critical role in the immune system, which includes three subgroups of T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in lymphopoiesis has revolutionized our understanding of the regulatory ...
Hamed Baghdadi   +8 more
doaj   +1 more source

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