Results 111 to 120 of about 13,099 (221)

Myeloid sarcoma: an uncommon presentation of myeloid neoplasms; a case series of 4 rare cases reported in a tertiary care institute

Autopsy and Case Reports, 2021
Myeloid sarcoma (MS) is a rare extramedullary neoplasm of myeloid cells, which can arise before, concurrently with, or following hematolymphoid malignancies.
Toyaja Jadhav, Puneet Baveja, Arijit Sen   +2 more
doaj  

Association of HLA antigens and BCR-ABL transcripts in leukemia patients with the Philadelphia chromosome

Revista Brasileira de Hematologia e Hemoterapia, 2012
OBJECTIVE: This study aimed to verify the association between human leukocyte antigens and the bcr-abl fusion protein resulting from t(9;22)(q34;q11) in chronic leukemia myeloid and acute lymphoblastic leukemia patients.
Daiana Landenberger de Carvalho, Cristian Dias Barbosa, André Luiz de Carvalho, Sandra Trevisan Beck   +3 more
doaj   +1 more source

Neue Ansätze des molekularen Targetings bei der Philadelphia-Chromosom-positiven Leukämie

, 2011
In Philadelphia Chromosome (Ph) positive ALL and CML the fusion between BCR and ABL leads to the BCR/ABL fusion proteins, which induces the leukemic phenotype because of the constitutive activation of multiple signaling pathways down-stream to the ...
Mian, Afsar Ali
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Ultra-deep mutational analysis of NPM-ALK and possible implications on target therapy in anaplastic large cell lymphoma of childhood [PDF]

, 2013
Anaplastic Large Cell Lymphoma (ALCL) represents a distinct subset of aggressive T-cell non-Hodgkin lymphoma (NHL) accounting for about 3% of adult NHL and 10 to 15% of childhood lymphomas.
Lovisa, Federica
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Avaliação do potencial mielossupressor do mesilato de imatinibe sobre células progenitoras hematopoiéticas e células do estroma da medula óssea de camundongos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-graduação em Farmácia, Florianópolis, 2009.Os agentes antineoplásicos atingem células que estão em processo de divisão celular, assim, a rápida ...
Soares, Pâmela de Brum
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BCR-ABL Tyrosine Kinase Domain Mutations Combinations Affects Imat inib Resistence in Chronic Phase Chronic Myelogenous Leukemia [PDF]

, 2019
Background: Chronic myelogenous leukemia is a myeloproliferative disease, due to reciprocal translocations of chromosome 9 and 22, resulting to Bcr-Abl fusion gene.
Amrita P N A, Siprianus Ugroseno Yudho Bintoro, Soebandiri S, Suryohusodo P, Endang Joewarini   +4 more
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Análise dos efeitos do mesilato de imatinibe em cultura de células-tronco mesenquimais humanas derivadas de placenta [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2011Apesar do recente avanço e evolução no desenvolvimento de medicamentos cada vez mais específicos para
Marostica, Lucas Lourenço
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MK-0457, an Aurora kinase and BCR-ABL inhibitor, is active in patients with BCR-ABL T315I leukemia

, 2013
MK-0457, an Aurora kinase and BCR-ABL inhibitor, was studied on a Phase I/II study in 77 patients with refractory hematologic malignancies. The average number of cycles per patient was 3 (range 1-21).
Zhao, B, Freedman, S J, Swords, R T, Cortes, J E, Rizzieri, D A, Hochhaus, A, Watson, P, Clark, J, Bergstrom, D, Le Coutre, P D, Giles, F J, Nagler, A, Xiao, A, Ottmann, O G, Talpaz, M   +14 more
core   +1 more source

Philadelphia Chromosome-negative, bcr/abl-positive Chronic Myelogenous Leukemia.

Journal of Nippon Medical School, 2001
Inokuchi, Koiti, Dan, Kazuo
openaire   +3 more sources

Untersuchungen zur Regulierung und Funktion der Mitogen-aktivierten Proteinkinase ERK5 = Regulation and Function of the Mitogen-activated Protein Kinase ERK5

, 2003
Mitogen activated protein kinases (MAPKs) are found in all eukaryotic cells and represent crucial elements in the signal transduction from the plasma membrane to the nucleus.
Buschbeck, Marcus
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