Development of pediatric myeloid leukemia may be related to the repeatedbone-remodeling during bone-growth [PDF]
arXiv, 2018 Acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) are two major formsof leukemia developed from myeloid cells (MCs). To understand why AML and CML occurin children, we analyzed the causes and the mechanism of cell transformation of a MC. I.
arxiv
BCR-ABL mutational studies for predicting the response of patients with chronic myeloid leukaemia to second-generation tyrosine kinase inhibitors after imatinib fail [PDF]
, 2009 Imatinib is the standard treatment for chronic myeloid leukaemia. BCR-ABL kinase domain mutation is the commonest mechanism implicated in imatinib resistance. In in-vitro studies, kinase domain mutations are variably resistant to second-line agents.
Chan, YY +8 more
core
A tumor-immune model of chronic myeloid leukemia with optimal immunotherapeutic protocols [PDF]
arXivThe interactions between tumor cells and the immune system play a crucial role in cancer evolution. In this study, we explore how these interactions influence cancer progression by modeling the relationships among naive T cells, effector T cells, and chronic myeloid leukemia cells. We examine the existence of equilibria, the asymptotic stability of the
arxiv
Identification and Counting White Blood Cells and Red Blood Cells using Image Processing Case Study of Leukemia [PDF]
arXiv, 2015 Leukemia is diagnosed with complete blood counts which is by calculating all blood cells and compare the number of white blood cells (White Blood Cells / WBC) and red blood cells (Red Blood Cells / RBC). Information obtained from a complete blood count, has become a cornerstone in the hematology laboratory for diagnostic purposes and monitoring of ...
arxiv
A mathematical model of clonal hematopoiesis explaining phase transitions in myeloid leukemia [PDF]
arXivThis study presents a mathematical model describing cloned hematopoiesis in chronic myeloid leukemia (CML) through a nonlinear system of differential equations. The primary objective is to understand the progression from normal hematopoiesis to the chronic and accelerated-acute phases in myeloid leukemia.
arxiv
Novel prognostic factors in chronic myeloid leukemia [PDF]
, 2008 Chronic myeloid leukemia (CML) is a malignant clonal blood disease that originates from a pluripotent hematopoietic stem cell. The cytogenetic hallmark of CML, the Philadelphia chromosome (Ph), is formed as a result of reciprocal translocation between ...
Lundán, Tuija
core
Philadelphia Chromosome-negative, bcr/abl-positive Chronic Myelogenous Leukemia.
Journal of Nippon Medical School, 2001 Koiti Inokuchi, Kazuo Dan
openaire +4 more sources
Immunocytochemical study of BCR and bcr-abl localization in K562 cells [PDF]
, 2010 Aim: To obtain polyclonal antibodies against recombinant proteins recognizing Bcr domain and fusion region of Bcr-Abl and analyze the patterns of intracellular distribution of Bcr and Bcr-Abl proteins in K562 cells of chronic myelogenous leukemia ...
Dubrovska, A.N. +6 more
core