Although bcr-abl polymerase chain reaction (PCR) positivity after bone marrow transplantation (BMT) for chronic myelogenous leukemia (CML) is significantly related to relapse, the predictive value of the assay is not very high and therefore most investigators consider that qualitative RT-PCR data alone are too imprecise to enable clinical decisions to ...
J, Román+10 more
openaire +1 more source
Reverse Degree-Based Topological Indices and QSPR Analysis of Cancer Drugs [PDF]
A topological index of a graph $G$ is a numerical quantity that describes its topology. Reverse degree-based topological indices play an important role in finding topological descriptors. Azacitidine, Decitabine, and Guadecitabine are hypomethylating agents which are used for the treatment of patients with higher-risk myelodysplastic syndromes, acute ...
arxiv
Several groups have shown that Ph-progenitors reappear in LTC of CML bone marrow or PBMNC when the cell preparations were derived from newly diagnosed Ph-positive patients or after induction chemotherapy. We have tested the hypothesis whether LTC may further decrease CML progenitors if the cells to be cultured were from IFN-treated patients.
B, Schultheis+4 more
openaire +1 more source
ULV: A robust statistical method for clustered data, with applications to multisubject, single-cell omics data [PDF]
Molecular and genomic technological advancements have greatly enhanced our understanding of biological processes by allowing us to quantify key biological variables such as gene expression, protein levels, and microbiome compositions. These breakthroughs have enabled us to achieve increasingly higher levels of resolution in our measurements ...
arxiv
New onset diabetes manifesting as diabetic ketoacidosis in a patient with chronic myelogenous leukemia treated with imatinib. [PDF]
Salimova D+4 more
europepmc +1 more source
Treatment of <i>JAK2</i> V617F-positive primary myelofibrosis and advanced chronic myelogenous leukemia with ruxolitinib and flumatinib: a case report. [PDF]
Zhu F, Wang H, Qiu L.
europepmc +1 more source
The road not taken: Exploring non-transplant options in De Novo philadelphia positive acute myeloid leukemia. [PDF]
Sharif MI+6 more
europepmc +1 more source
Chronic myelogenous leukemia coexpressing V-e16a2, V-e13a2, e13a2, and e14a2 BCR::ABL1 fusion transcripts: a case report and review of the literature. [PDF]
Xu Y+9 more
europepmc +1 more source
Cardiac arrhythmias of BCR-ABL inhibitors with or without triazole antifungal agents: A real-world pharmacovigilance study based on the food and drug administration adverse event reporting system database. [PDF]
Xie P+5 more
europepmc +1 more source
Co-Occurrence of Jak2-Positive Myelofibrosis and Bcr-Abl-Positive Chronic Myelogenous Leukaemia Treated with Combination of Tyrosine Kinase Inhibitors and Ruxolitinib. [PDF]
Paciaroni K+8 more
europepmc +1 more source