Results 101 to 110 of about 305,001 (288)

Comparative analysis of blood lymphocytes of patients with acute and chronic myeloid leukemia by surface and intracellular α1-acid glycoprotein and fibronectin

Біологічні студії, 2014
The exposition of α1-acid glycoprotein and fibronectin on the surface and inside the lymphocytes of healthy donors and hematological patients with acute and chronic myeloid leukemia were studied.
G. S. Маslak
doaj   +1 more source

Genomic landscapes and clonality of de novo AML [PDF]

, 2013
No abstract ...
Brewin, John, Chevassut, Timothy, Horne, Gillian   +2 more
core   +1 more source

Age and acute myeloid leukemia

Blood, 2006
We conducted a retrospective analysis of 968 adults with acute myeloid leukemia (AML) on 5 recent Southwest Oncology Group trials to understand how the nature of AML changes with age. Older study patients with AML presented with poorer performance status, lower white blood cell counts, and a lower percentage of marrow blasts.
Frederick R, Appelbaum, Holly, Gundacker, David R, Head, Marilyn L, Slovak, Cheryl L, Willman, John E, Godwin, Jeanne E, Anderson, Stephen H, Petersdorf   +7 more
openaire   +3 more sources

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms [PDF]

, 2011
Background: Alterations in the DNA methylation pattern are a hallmark of leukemias and lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have focused either on the analysis of few candidate genes or many genes and few HN entities,
Agirre, Xabier, Alvarez, Sara, Ammerpohl, Ole, Bibikova, Marina, Brüggemann, Monika, Bug, Stefanie, Calasanz, Maria J., Cruz Cigudosa, Juan, Deckert, Martina, Dreyling, Martin, Du, Ming Q., Dyer, Martin J. S., Dürig, Jan, Fan, Jian-Bing, Gesk, Stefan, Haferlach, Claudia, Hansmann, Martin-Leo, Harder, Lana, Hartmann, Sylvia, Klapper, Wolfram, Küppers, Ralf, Martin-Subero, Jose Ignacio, Montesinos-Rongen, Manuel, Nagel, Inga, Pott, Christiane, Prosper, Felipe, Richter, Julia, Román-Gómez, José, Seifert, Marc, Siebert, Reiner, Stein, Harald, Suela, Javier, Trümper, Lorenz, Vater, Inga, Wickham-Garcia, Eliza   +34 more
core  

Gene rearrangements in bone marrow cells of patients with acute myelogenous leukemia [PDF]

, 2000
At diagnosis, clonal gene rearrangement probes {[}retinoic acid receptor (RAR)-alpha, major breakpoint cluster region (M-bcr), immunoglobulin (Ig)-JH, T cell receptor (TcR)-beta, myeloid lymphoid leukemia (MLL) or cytokine genes (GM-CSF, G-CSF, IL-3 ...
Braun, S., Duell, T., Gerhartz, Helmut Heinrich, Mittermueller, J., Schmetzer, Helga Maria, Wiesner, D.   +5 more
core   +1 more source

CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1

Advanced Science, EarlyView.
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang, Xin Yang, Lei Xing, Hang Chen, Fuming Xie, Bin Wang, Bowen Shi, Yan Yang, Junxia Chen   +8 more
wiley   +1 more source

Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells. [PDF]

, 2017
Aberrant cytokine signaling initiated from mutant receptor tyrosine kinases (RTKs) provides critical growth and survival signals in high risk acute myeloid leukemia (AML).
Arbiser, Jack L, Bradley, Heath L, Bunting, Kevin D, Kapur, Reuben, Metts, Jonathan, Shah, Neil P, Wang, Zhengqi   +6 more
core   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, EarlyView.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

Anterior myeloid sarcoma revealing acute myeloid leukemia: Case report

Egyptian Journal of Chest Disease and Tuberculosis, 2016
Myeloid sarcoma (MS) is a tumor mass of myeloblasts or immature myeloid cells occurring in an extramedullary site or in the bone and generally precedes or reveals myeloid leukemia. It rarely occurs in the mediastinum.
H. Slimani, L. Achaachi, Y. Benbaba, L. Herrak, K. Znati, M. Ftouh   +5 more
doaj   +1 more source