Results 181 to 190 of about 305,001 (288)

The Prognostic Value of Integrating Copy Number Alteration Profiles in <i>NPM1</i>-Mutated Acute Myeloid Leukemia: An Exploratory Study. [PDF]

Appl Clin Genet
Zhang C, Gao L, Gong M, Liu C, Zhang D, Li Z.   +5 more
europepmc   +1 more source

A phase 2 study incorporating sorafenib into the chemotherapy for older adults with FLT3-mutated acute myeloid leukemia: CALGB 11001 [PDF]

, 2017
Uy, Geoffrey L., Westervelt, Peter
core   +1 more source

Transcriptomic Diversity of Pediatric Acute Myeloid Leukemia Genetic Drivers Correlates With Clinical Outcome and Expression of Stemness-Related Genes. [PDF]

Cancer Med
Bubb QR, Sotillo E, Richards RM, Mackall CL, Gruber TA, Czechowicz A.   +5 more
europepmc   +1 more source

Childhood acute leukemia and type 1 diabetes in children: A nationwide case–control study

International Journal of Cancer, EarlyView.
What's New? The etiology of childhood acute leukemia remains poorly understood. Accumulating evidence suggests a potential link between leukemia and autoimmune diseases. This nationwide, register‐based case–control study investigated the association between childhood acute leukemia and type 1 diabetes in Finland.
Julia Ventelä, Ida Pellikka, Anssi Auvinen, Olli Lohi, Atte Nikkilä   +4 more
wiley   +1 more source

Secondary Acute Myeloid Leukemia in Treatment-Naïve Primary Testicular Diffuse Large B-Cell Lymphoma. [PDF]

Case Rep Hematol
Wan Hanafi HH, Mohd Sabri NM, Muhamat Yusoff R, Nizam Akbar NA, Mohd Noor NH, Hussain FA, Husin A.   +6 more
europepmc   +1 more source

Integrated scFv identification and CAR T cell generation for AML targeting in vivo

International Journal of Cancer, EarlyView.
What's New? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu, Annika Lauk, David Sedloev, Josephine Brysting, Ela Cetin, Chunan Liu, Maximilian Mönnig, Thomas Luft, Haiyang Yun, Michael Schmitt, Tim Sauer, Fengbiao Zhou, Christian Rohde, Carsten Müller‐Tidow   +13 more
wiley   +1 more source

Tumor‐infiltrating B cells participate in shaping the immunosuppressive microenvironment in solid tumors

International Journal of Cancer, EarlyView.
Abstract Tumor‐infiltrating B cells (TIBs) exhibit dual roles in the tumor microenvironment (TME) of solid tumors. While they can enhance anti‐tumor immunity through antibody production and immune activation, certain subsets—such as regulatory B cells (Bregs) and immunosuppressive plasma cells—contribute to immune evasion by secreting inhibitory ...
Zhitong Li, Ziyang Shen, Yuxiang Sun, Pengcheng Zhu, Tongyan Liu, Rong Yin   +5 more
wiley   +1 more source

Arsenic Sulfide Induces Apoptosis in Myelodysplastic Neoplasm Cells Through the Suppression of ABI2. [PDF]

Biol Proced Online
Tao Y, Ding N, Ni R, Cai S, Jin R, Chen Y, Ren J, Xu H, Ba Q, Lu J.   +9 more
europepmc   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Leveraging genomic diagnostics for prognostics and therapeutics in pediatric acute leukemia. [PDF]

Hemasphere
Newman H, Wong D, Wu J, Schubert J, Golenberg N, Naveh N, Patel M, Xu F, Charles S, Chen J, Denenberg EH, Fanning EA, Gallo D, Luke T, Thomas M, Cao K, Chan AJS, Holloman M, Fan Z, Fu W, Hunger SP, MacFarland SP, Bernt KM, Surrey LF, Luo M, Wertheim GB, Li MM, Tasian SK, Zhong Y.   +28 more
europepmc   +1 more source