Results 211 to 220 of about 305,001 (288)

Rib Ewing Sarcomas in Children and Young Adults: A Large National Retrospective Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Purpose Ewing sarcoma (ES) is the most prevalent malignant thoracic tumor in childhood and young adults. This study reports the outcome of a national cohort treated in an international prospective trial for a localized rib ES, with a long follow‐up.
Audrey Claren   +14 more
wiley   +1 more source

Patient and Family Demographics in the Momcology Pediatric Cancer Patient Advocacy Organization

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Momcology is a US‐based patient advocacy organization that provides support for families of children with cancer. This study describes Momcology for researchers by detailing the demographic, clinical, and socioeconomic (socioeconomic status [SES]) data within its registry and comparing it to the National Surveillance, Epidemiology ...
Ryan Salama   +6 more
wiley   +1 more source

Determining Preclinical Safety of Aclarubicin in Pediatric Malignancies

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Anthracyclines are among the most effective chemotherapeutic agents used to treat pediatric malignancies. However, their clinical use is limited by dose‐dependent toxicities, particularly cardiotoxicity and secondary malignancies.
Darleen S. Tu   +15 more
wiley   +1 more source

Allogeneic hematopoietic stem cell transplantation for mixed-phenotype acute leukemia: a single-center study. [PDF]

open access: yesFront Immunol
Hao M   +10 more
europepmc   +1 more source

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak   +7 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

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