Results 171 to 180 of about 1,294,431 (344)

Phosphorylation‐Dependent Stabilization of Collaborator of ARF (CARF) Suppresses Lymphoma Cell Proliferation

open access: yesAdvanced Science, EarlyView.
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu   +7 more
wiley   +1 more source

Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia

open access: yesHaematologica, 2015
Manja Meggendorfer   +9 more
doaj   +1 more source

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang   +11 more
wiley   +1 more source

Risk of early death after acute leukemia diagnosis among adolescents and young adults. [PDF]

open access: yesJNCI Cancer Spectr
Berkman AM   +18 more
europepmc   +1 more source

Effects of intravenous vaccinia in mice with sarcoma 180 or leukemia 9417 [PDF]

open access: bronze, 1950
Joseph C. Turner, B. Mulliken
openalex   +1 more source

NIR Driven Pd/Cerium Oxide Nano‐Heterojunction for Enhanced Salvaging Sepsis Induced Acute Liver Injury via Reprogramming Redox Homeostasis in Synergy with Inducing Autophagy

open access: yesAdvanced Science, EarlyView.
In vivo SALI therapy is achieved by scavenging intracellular ROS levels, downregulating inflammatory factors expression levels, inducing macrophage M2 directional polarization, and activating Keap1/Nrf‐2/HO‐1 pathway to reprogram redox homeostasis, induce cellular autophagy, reduce systemic inflammation, and promote liver tissue repair. Abstract Sepsis
Tao Qin   +21 more
wiley   +1 more source

Case Report: Chronic Granulocytic (Myelogenous) Leukemia and Pregnancy [PDF]

open access: bronze, 1953
Harold Shub   +2 more
openalex   +1 more source

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