Results 171 to 180 of about 554,772 (269)

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

Opinion: a call for safe therapeutic and gastric interventions for adolescents and young adults with obesity and transplant-indicated leukemia. [PDF]

Front Oncol
Garcia MB, Perales P, Santos D, Tzeng CD, Cuglievan B, Sheikh IN.   +5 more
europepmc   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Oral Leukemia Cutis and Facial Sweet's Syndrome Associated with Acute Myeloid Leukemia.

Indian J Dermatol
Manzone SZ, Anderlini C, Salduna D, Calafat P, Kurpis M, Valente E.   +5 more
europepmc   +1 more source

Clinico-Hematological and Immunophenotypic Profile of Leukemia Patients at a Tertiary Care Center in Jharkhand, India: A Cross-Sectional Study. [PDF]

Cureus
Shome A, Paswan MK, Jamaiyar A, Shome A.
europepmc   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Peripherally inserted central venous catheters for remission induction chemotherapy phase of acute leukemia: a single center experience in severely thrombocytopenic patients. [PDF]

Ann Hematol
Picardi M, Giordano C, Vincenzi A, Scarpa A, Pugliese N, Della Pepa R, Cimmino E, Persico M, Pane F.   +8 more
europepmc   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source