Results 231 to 240 of about 1,294,431 (344)
Serum Anti-Proteases in the Leukemias [PDF]
Philip M. West, BETTY W. SMITH
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Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao+8 more
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Isolated Central Nervous System Presentation of Early T-Cell Precursor Acute Lymphoblastic Leukemia/Lymphoma: A Rare Case of Exclusive Brain Involvement. [PDF]
Swart VO, Zoghi B.
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CARBAMATES IN THE CHEMOTHERAPY OF LEUKEMIA [PDF]
Howard E. Skipper+3 more
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This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen+11 more
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One step further in targeting acute leukemia by combining antibody-based immunotherapies and small molecule inhibitors. [PDF]
Dozandeh-Jouybari A+7 more
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The findings suggest that the combination of PIM‐2 and PARP1 inhibitors can induce MICA expression on MM cells, thereby activating NK cells through NKG2D binding. This process may restore NK cell function and serve as a potential therapeutic approach for MM patients. Abstract While immunogenic death in tumor cells activates specific anti‐tumor T cells,
Zhaoyun Liu+6 more
wiley +1 more source
Periplocin Targets HDAC10 to Inhibit NF-κB Signaling and Induce Apoptosis in Myeloid Leukemia Cells. [PDF]
Li W+6 more
europepmc +1 more source