Results 231 to 240 of about 1,245,695 (368)

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

Advanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu, Yaochang Wei, Yuelin Li, Yiming Dou, YongQiang Yang, Hanghang Liu, Xiaoyan Wang, Zheng Wang, Jianmin Su, Yong Zhang, Yongsheng Wang   +10 more
wiley   +1 more source

Isatuximab plus carfilzomib and dexamethasone in patients with relapsed multiple myeloma based on prior lines of treatment and refractory status: IKEMA subgroup analysis

, 2023
American Journal of Hematology, Volume 98, Issue 1, Page E15-E19, January 2023.
Meletios A. Dimopoulos, Philippe Moreau, Bradley Augustson, Nelson Castro, Tomas Pika, Sosana Delimpasi, Javier De la Rubia, Angelo Maiolino, Tony Reiman, Joaquin Martinez‐Lopez, Thomas Martin, Joseph Mikhael, Kwee Yong, Marie‐Laure Risse, Gaelle Asset, Sylvia Marion, Roman Hajek   +16 more
wiley   +1 more source

Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia

American Journal of Hematology, Volume 98, Issue 2, Page 338-347, February 2023., 2023
Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo, Christian Buske, Judith Trotman, Shayna Sarosiek, Steven P. Treon   +4 more
wiley   +1 more source

IS LEUKEMIA A DISEASE OF THE RETICULO-ENDOTHELIAL SYSTEM? [PDF]

, 1948
Bruce K. Wiseman
openalex   +1 more source

Leukemia

Current Opinion in Oncology, 1997
openaire   +6 more sources

MRAS: Master Regulator Analysis of Alternative Splicing

Advanced Science, EarlyView.
This study developed a computational approach called MRAS, designed to identify master regulators of splicing differences across various biological contexts. In this framework, altered RBP expression, rather than spliceosomal mutations or other modifications, plays a central role in driving these splicing differences.
Lei Zhou, Yue Huang, Yang Zhao, Dan Guo, Xiao Wen, Ruihong Xu, Xuan Lv, Song Wu, Sicheng Jing, Zhaoqi Liu   +9 more
wiley   +1 more source

Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia

Haematologica, 2015
Manja Meggendorfer, Andreia de Albuquerque, Niroshan Nadarajah, Tamara Alpermann, Wolfgang Kern, Kimberly Steuer, Karolína Perglerová, Claudia Haferlach, Susanne Schnittger, Torsten Haferlach   +9 more
doaj   +1 more source

STUDIES ON MOUSE LEUKEMIA [PDF]

, 1934
Joseph Victor, James S. Potter
openalex   +1 more source

Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia

New England Journal of Medicine, 2017
H. Kantarjian, A. Stein, N. Gökbuget, A. Fielding, A. Schuh, J. Ribera, A. Wei, H. Dombret, R. Foà, R. Bassan, Ö. Arslan, M. Sanz, J. Bergeron, F. Demirkan, E. Lech-Maranda, A. Rambaldi, X. Thomas, H. Horst, M. Brüggemann, W. Klapper, B. Wood, A. Fleishman, D. Nagorsen, C. Holland, Z. Zimmerman, M. Topp   +25 more
semanticscholar   +1 more source

Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

Advanced Science, EarlyView.
When the normal kidney is subjected to injurious stimuli, it can lead to persistent activation of ATG5. The activation of ATG5 promotes HSP90‐HIF‐1α interaction, resulting in stabilization of HIF‐1α and subsequent activation of glycolysis. Consequently, this process contributes to mitochondrial fission and inflammation, ultimately culminating in kidney
Yan Hu, Jinqing Li, Hui Chen, Yingfeng Shi, Xiaoyan Ma, Yi Wang, Xialin Li, Qin Zhong, Yishu Wang, Daofang Jiang, Shougang Zhuang, Na Liu   +11 more
wiley   +1 more source