Results 241 to 250 of about 1,111,327 (316)

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

Advanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen, Zhen Li, Jiajia Shen, Jingyu Lin, Xiaoli Zhao, Rui Zhang, Ying Han, Zhen Wang   +7 more
wiley   +1 more source

Myeloid dermatosis with features of sweet syndrome and leukemia cutis: a case report. [PDF]

Ann Hematol
Patel E, Singh A, Beach D, Morrissette J, Caponetti G.   +4 more
europepmc   +1 more source

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

Advanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su, Qi Qi, Yi Fan, Yubo Wang, Gaoyang Hao, Ka‐Chun Wong, Yunhe Wang, Xiangtao Li   +7 more
wiley   +1 more source

The structure and functions of TRAF families and recent advances of TRAFs in leukemia. [PDF]

Front Oncol
Gao L, Yan M, Xu R, Xu L, Song Y, Li W, Li X.   +6 more
europepmc   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Dendritic cells in hematologic malignancies: a brief review of immunoregulation to new perspectives. [PDF]

Biochem Med (Zagreb)
de Almeida GB, Dos Santos MM, de Oliveira Barbosa D, Conceição RR, de Almeida Lopes B, de Melo Santos HH, Marchioro SB.   +6 more
europepmc   +1 more source

Proximally biased V(D)J recombination in the clonal evolution of IGH alleles in KMT2A::AFF1 BCP‐ALL of all age classes

HemaSphere
Heiko Müller, Frank Dicker, Constance Bär, Wencke Walter, Stephan Hutter, Niroshan Nadarajah, Manja Meggendorfer, Qingsong Gao, Ilaria Iacobucci, Charles G. Mullighan, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach   +12 more
doaj   +1 more source

The Efficiency of Allotransplant in a Case of Acute Biphenotypic Myeloid and B-Lymphoid Leukemia (MPAL Myelo/B NOS) That Presented Concurrently with a Mediastinal Granulocytic Sarcoma Co-Expressing Lymphoid Markers Complicated by Cardiac Tamponade. [PDF]

Diagnostics (Basel)
Catana AC, Lazar Benedek E, Zaharie I, Mocanu L, Mera G, Popa C, Mondoc LM.   +6 more
europepmc   +1 more source

Acute genital ulceration in a 14-month-old girl with <i>rhinovirus</i> infection and new onset B-cell acute lymphoblastic leukemia. [PDF]

JAAD Case Rep
Andre M, Purvis C, Motaparthi K.
europepmc   +1 more source

Long-Term Clinical Consequences of Severe Oral Mucositis in Survivors of Lip, Oral Cavity, and Pharynx Cancer Versus Leukemia: A Propensity-Score-Matched Comparative Cohort Study Using Real-World Data. [PDF]

Med Sci (Basel)
Satheeshkumar PS, Gopalakrishnan V, Epstein JB, Pili R.   +3 more
europepmc   +1 more source