Results 261 to 270 of about 1,111,327 (316)
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“Atypical” Leukemias: Preleukemia, Smoldering Leukemia and Hypoplastic Leukemia
1984The term “atypical leukemia” covers a wide range of heterogeneous disorders whose classification has hitherto been controversial. This controversy has arisen from the use of different criteria for the definition of the various entities. The application of morphological criteria has led to the separation of conditions without recognizable leukemic ...
D, Hoelzer, A, Ganser, H, Heimpel
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Seminars in Oncology, 2006
T and B subtypes of prolymphocytic leukemias (PLLs) are rare, highly aggressive lymphoid malignancies with characteristic morphologic, immunophenotypical, cytogenetic, and molecular features. Recent studies have highlighted the role of specific oncogenes such as TCL1, MTCP-1, and ATM in the case of T-cell and p53 mutations in the case of B-cell PLLs ...
Krishnan, B, Matutes, E, Dearden, C
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T and B subtypes of prolymphocytic leukemias (PLLs) are rare, highly aggressive lymphoid malignancies with characteristic morphologic, immunophenotypical, cytogenetic, and molecular features. Recent studies have highlighted the role of specific oncogenes such as TCL1, MTCP-1, and ATM in the case of T-cell and p53 mutations in the case of B-cell PLLs ...
Krishnan, B, Matutes, E, Dearden, C
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Clinics in Perinatology, 2021
Neonates are at risk for 3 major forms of leukemia in the first year of life: acute leukemia, juvenile myelomonocytic leukemia, and transient abnormal myelopoiesis associated with Down syndrome. These disorders are rare but generate interest due to aggressive clinical presentation, suboptimal response to current therapies, and fascinating biology. Each
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Neonates are at risk for 3 major forms of leukemia in the first year of life: acute leukemia, juvenile myelomonocytic leukemia, and transient abnormal myelopoiesis associated with Down syndrome. These disorders are rare but generate interest due to aggressive clinical presentation, suboptimal response to current therapies, and fascinating biology. Each
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Pediatrics, 1970
The paper by Dr. Finklestein and others,1 leaves one with the impression that testicular involvement in acute leukemia, an almost general finding at post mortem, is an uncommon clinical problem. We wonder whether lack of awareness might not be responsible for this, as our own experience suggests.
F, Leef, G, Kende, B, Ramot
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The paper by Dr. Finklestein and others,1 leaves one with the impression that testicular involvement in acute leukemia, an almost general finding at post mortem, is an uncommon clinical problem. We wonder whether lack of awareness might not be responsible for this, as our own experience suggests.
F, Leef, G, Kende, B, Ramot
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Hematology/Oncology Clinics of North America, 1990
PLL is an unusual clinical and morphologic variant of CLL which, in the more common B cell version, represents malignant transformation of a B lymphocyte at an intermediate stage of development. The immunophenotype of PLL cells, characterized by heavy cell surface staining for IgM and/or IgD and loss of mouse red blood cell receptors, suggests ...
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PLL is an unusual clinical and morphologic variant of CLL which, in the more common B cell version, represents malignant transformation of a B lymphocyte at an intermediate stage of development. The immunophenotype of PLL cells, characterized by heavy cell surface staining for IgM and/or IgD and loss of mouse red blood cell receptors, suggests ...
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Blood, 1951
Abstract Four new cases of congenital leukemia reported here may be added to the 14 acceptable cases in the literature. In all except 1 of these cases cells of the granulocytic series were involved; males predominated over females in a ratio of more than 2 to 1.
W G, BERNHARD, I, GORE, R A, KILBY
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Abstract Four new cases of congenital leukemia reported here may be added to the 14 acceptable cases in the literature. In all except 1 of these cases cells of the granulocytic series were involved; males predominated over females in a ratio of more than 2 to 1.
W G, BERNHARD, I, GORE, R A, KILBY
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Critical Care Nursing Clinics of North America, 2013
The chronic leukemias include chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL). CML is a clonal myeloproliferative hematopoietic stem-cell disorder, and CLL is a monoclonal B-cell disorder. CML is Philadelphia chromosome positive. There are 3 phases of CML: the chronic phase, the accelerated phase, and the blast phase.
Edythe M Lyn, Greenberg +1 more
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The chronic leukemias include chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL). CML is a clonal myeloproliferative hematopoietic stem-cell disorder, and CLL is a monoclonal B-cell disorder. CML is Philadelphia chromosome positive. There are 3 phases of CML: the chronic phase, the accelerated phase, and the blast phase.
Edythe M Lyn, Greenberg +1 more
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Current Treatment Options in Oncology, 2015
Familial leukemia has been described for more than 50 years but only recently have modern genetic techniques allowed for the investigation of the genome. Genome-wide association studies have identified a number of genetic sites that appear to relate to susceptibility to leukemia in certain families and occasionally to susceptibility to a specific ...
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Familial leukemia has been described for more than 50 years but only recently have modern genetic techniques allowed for the investigation of the genome. Genome-wide association studies have identified a number of genetic sites that appear to relate to susceptibility to leukemia in certain families and occasionally to susceptibility to a specific ...
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Clinics in Laboratory Medicine, 2002
This article provides a review of the acute leukemias with updated basic and practical information. The main emphasis is on techniques used to arrive at the correct diagnosis. Although morphology and cytochemistry were the mainstays of diagnosis in the past, new developments in immunophenotyping, cytogenetics, molecular biology, and in vitro assays ...
Harold R, Schumacher +3 more
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This article provides a review of the acute leukemias with updated basic and practical information. The main emphasis is on techniques used to arrive at the correct diagnosis. Although morphology and cytochemistry were the mainstays of diagnosis in the past, new developments in immunophenotyping, cytogenetics, molecular biology, and in vitro assays ...
Harold R, Schumacher +3 more
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Southern Medical Journal, 1980
We have described a patient with basophilic leukemia secondary to chronic granulocytic leukemia. Symptoms of hyperhistaminemia were aggravated after chemotherapy with hydroxyurea. Antihistamines (H1 receptor antagonists) controlled many of the symptoms related to hyperhistaminemia.
C V, Jennings, C L, Dannaher, L T, Yam
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We have described a patient with basophilic leukemia secondary to chronic granulocytic leukemia. Symptoms of hyperhistaminemia were aggravated after chemotherapy with hydroxyurea. Antihistamines (H1 receptor antagonists) controlled many of the symptoms related to hyperhistaminemia.
C V, Jennings, C L, Dannaher, L T, Yam
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