Results 151 to 160 of about 4,796,691 (248)

Investigating the Role of Anti-Leukemia Inhibitory Factor Antibody on Cytokine Profile in a Mouse Model of Breast Cancer. [PDF]

Cancer Rep (Hoboken)
Seifati SM, Hadinedoushan H, Ansariniya H, Zare F.   +3 more
europepmc   +1 more source

The Molecular Basis and Therapeutic Potential of Leukemia Inhibitory Factor in Cancer Cachexia. [PDF]

Cancers (Basel), 2022
Zeng R, Tong C, Xiong X.
europepmc   +1 more source

Epigenetic Reactivation of TNFRSF19 Suppresses Mitophagy and Sensitizes Triple‐Negative Breast Cancer to Doxorubicin

Advanced Science, EarlyView.
TNFRSF19 is an epigenetically silenced regulator of mitophagy in triple‐negative breast cancer. TNFRSF19 deficiency activates the TGFBR1–SMAD3–PINK1 axis to promote mitophagy and confer doxorubicin resistance, whereas decitabine‐mediated restoration of TNFRSF19 suppresses mitophagy and enhances doxorubicin sensitivity, revealing a targetable epigenetic–
Shiyang Liu, Chenguang Liu, Weihong Zheng, Xiaofei Tong, Zhengwei Gui, Zonghong Lu, Sun Ieong, Lin Zhang   +7 more
wiley   +1 more source

The Role of Leukemia Inhibitory Factor in Attenuating Skeletal Muscle Atrophy: Mechanisms to Exercise Interventions. [PDF]

Cells
Jiang N, Wang S, Zhang J, Jia D.
europepmc   +1 more source

Protective effect of leukemia inhibitory factor on the retinal injury induced by acute ocular hypertension in rats. [PDF]

Exp Ther Med, 2023
Lv J, Gao R, Wang Y, Huang C, Wu R.
europepmc   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Interleukin-6 and leukemia inhibitory factor differentially modify embryonic disk composition in post hatching bovine embryos†. [PDF]

Biol Reprod
Oliver MA, Mercadante VRG, Ealy AD.
europepmc   +1 more source

Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma. [PDF]

Front Oncol, 2023
Di Giorgio C, Bellini R, Lupia A, Massa C, Bordoni M, Marchianò S, Rosselli R, Sepe V, Rapacciuolo P, Moraca F, Morretta E, Ricci P, Urbani G, Monti MC, Biagioli M, Distrutti E, Catalanotti B, Zampella A, Fiorucci S.   +18 more
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Leukemia inhibitory factor promotes human cholangiopathies, and its inhibition improves cholestasis in Abcb4-/- mice. [PDF]

Hepatol Commun
Di Giorgio C, Urbani G, Massa C, Marchianò S, Biagioli M, Bordoni M, Lachi G, Sensini B, Del Sordo R, Paniconi F, Giannelli E, Sette MR, Cari L, Morretta E, Monti MC, De Gregorio R, Sepe V, Zampella A, Lapitz A, Milkiewicz P, Milkiewicz M, Banales JM, Distrutti E, Fiorucci S.   +23 more
europepmc   +1 more source