Results 191 to 200 of about 155,017 (308)

Hybrid handcrafted and deep feature fusion for automated acute myeloid leukemia classification using TCMA-Net on a class-balanced dataset. [PDF]

Front Oncol
Alshehri OM, Mushtaq Z, Taha M, Ijaz M, Irfan M, Altayar MA, Jalal MM, Abu-Alghayth MH, Al Shmrany H, Eltayb Hassan E.   +9 more
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

The <i>NFIA::CBFA2T3</i> identifies a molecularly defined subgroup of acute erythroid leukemia/erythroid sarcoma. [PDF]

Front Oncol
Brunetti M, Andersen K, Tjønnfjord GE, Zeller B, Spetalen S, Munthe-Kaas MC, Osnes LTN, Os TT, Micci F.   +8 more
europepmc   +1 more source

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Nutritional Status Changes During Pediatric Acute Lymphoblastic Leukemia Treatment: A Study from a Tertiary Care Hospital in Pakistan. [PDF]

Clin Med Insights Pediatr
Imran S, Rai N, Masood MMS, Farooq W, Nadeem K.   +4 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Dual targeting of EZH2 and EZH1 drives exit of leukemia stem cells from quiescence and potentiates chemotherapy in acute myeloid leukemia

Blood Cancer Journal
Hiroki Akiyama, Yuki Nishida, Kyung Hee Chang, Andrea D. Bedoy, Muharrem Muftuoglu, Wencai Ma, Mahesh Basyal, Zoe Hirschi, Daisuke Honma, Shinji Tsutsumi, Jing Wang, Weiguo Zhang, Xuelin Huang, Raajit K. Rampal, Olalekan O. Oluwole, Dale Lee Bixby, Naval G. Daver, Michael Andreeff   +17 more
doaj   +1 more source

CD30 Expression in Acute Myeloid Leukemia : A Cross Sectional Study in Relapsed , Refractory and Ill Fated Acute Myeloid Leukemia

Ain Shams Medical Journal, 2013
Rasha A. Elgamal, Gehan Mostafa Hamed
openaire   +1 more source

Acute leukemia during pregnancy: a single center experience with 23 cases, 2012-2022 and literature review. [PDF]

Ann Med
Liu W, Guo J, Gai D, Zhang KX, Liu Y, Zhao XL, Fu X, Rosen ST, Chen C, Chen F.   +9 more
europepmc   +1 more source

Mitigating Teclistamab Toxicity: Prophylactic Tocilizumab and Timing of Immunoglobulin Replacement Therapy in a Nationwide Cohort

American Journal of Hematology, EarlyView.
Astrid Hundebøll Torpe, Jonathan Thorsen, Gustav Mathiasen, Katrine Fladeland Iversen, Sarah Farmer, Thomas Lund, Charlotte Toftmann Hansen, Lene Kongsgaard Nielsen, Nicolai Grønne Dahlager Jørgensen, Maja Ølholm Vase, Elena Manuela Teodorescu, Morten Salomo, Christina Wennerström, Tobias S. Slørdahl, Agoston Gyula Szabo   +14 more
wiley   +1 more source