A microfluidic bone marrow model combining CFD and organ-on-a-chip technologies to study leukemia niche dynamics. [PDF]
Rosalem GS +8 more
europepmc +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Determinants of survival in patients treated with CPX-351 for acute myeloid leukemia. [PDF]
Chiusolo P +10 more
europepmc +1 more source
Oocyte–cumulus cell interaction: a key factor in early embryo development
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido +2 more
wiley +1 more source
Prognostic Scores and Risk Stratification of Myeloproliferative Neoplasms: 2026 Updates. [PDF]
Al-Zubaidi N +3 more
europepmc +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
Fractal-fractional modeling of chronic myelogenous leukemia immune dynamics using Laguerre wavelets method. [PDF]
Khirsariya SR, Noori N.
europepmc +1 more source
Features the major cell type compositions among colon and liver metastasis. (A) The study design for single‐cell data analysis. (B) The annotated major cell types. Each type was labeled with a special color. (C) Dot plot of canonical marker genes for major cell types. (D) Bar plot of the percentage for each cell type in individuals. (E) Bar plot of the
Zhixun Zhao +10 more
wiley +1 more source
Concurrent therapy-related acute myeloid leukemia and lymph node tuberculosis following treatment for lung squamous cell carcinoma: a case report and literature review. [PDF]
Yu Y, Yang D, Chen X, Chen Y.
europepmc +1 more source
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis +2 more
wiley +1 more source

