Results 141 to 150 of about 1,530,725 (262)
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens +9 more
wiley +1 more source
Author and suject indexes for the The Bovine Practitioner and the Proceedings of the Annual Meetings, 1985 ...
Bovine Practitioners, American Association of
core +1 more source
Aphids efficiently ingest dsRNA, which persists in the midgut but is rapidly degraded by aphid nucleases when unprotected. Chitosan and LDH‐based formulations improve dsRNA stability, triggering RNAi activation. Despite this protection, gene knockdown remains variable, though the RNAi machinery is consistently activated.
Lisa Merkel +4 more
wiley +1 more source
Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai +14 more
wiley +1 more source
Virological perspectives of the current situation of oncogenic viruses in Egypt: a review
Oncogenic viruses play a pernicious role in the development of cancer, causing various tumors in humans and animals. These viruses are of public health importance in developing nations.
Alaa H. Ibrahim +2 more
doaj +1 more source
Lactoferrin and Nanotechnology: New Insights Into Glioblastoma Therapy
Current glioblastoma multiforme (GBM) management primarily relies on surgery, chemotherapy, and radiotherapy; however, therapeutic efficacy remains limited due to tumor invasiveness and restricted drug penetration across the blood–brain barrier. Lactoferrin (LF), an iron‐binding glycoprotein with receptor‐mediated transport capability, has emerged as a
Atena Abed, Javad Amini Mahabadi
wiley +1 more source
The high expression of PRMT7 enhances its interaction with DVL2 by methylating arginine residues on FOXK1/FOXK2. This process promotes the nuclear translocation of DVL2, thereby aberrantly activating the Wnt/β‐catenin signalling pathway, which ultimately drives the development of doxorubicin resistance in DLBCL.
Xiaoyan Zhao +7 more
wiley +1 more source
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi +6 more
wiley +1 more source
Mechanism of synthesis, release, receptor activation, uptake, and degradation of GABA in dorsal root ganglia (DRG). Left: GABA is synthesized from putrescine in satellite glial cells (SGCs). After being released by Best1 channel, it activates GABAA receptors in sensory neurons, producing a chloride current.
Natalie Jiménez‐Barrios +7 more
wiley +1 more source

