Results 101 to 110 of about 933,022 (336)
CD97 is a member of the EGF-TM7 family of adhesion G protein-coupled receptors (GPCRs) broadly expressed on leukocytes. CD97 interacts with several cellular ligands via its N-terminal epidermal growth factor (EGF)-like domains. To understand the biological function of CD97, monoclonal antibodies (mAbs) specific for individual EGF domains have been ...
Jörg Hamann+8 more
openaire +4 more sources
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras+19 more
wiley +1 more source
ANALYSIS OF LEUKOCYTIC EXTRACTS FROM GUINEA PIGS HYPER-SENSITIVE TO TUBERCULIN AND 2,4-DINITROCHLOROBENZENE [PDF]
Wayburn S. Jeter+2 more
openalex +1 more source
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila+7 more
wiley +1 more source
On the Interaction of Dead Leukocytic Nuclei, L.E. Factor and Living Leukocytes in the L. E. Cell Phenomenon [PDF]
Daniel J. Nathan, I. Snapper
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao+6 more
wiley +1 more source
Studies on the Fibrinogen, Dextran and Phytohemagglutinin Methods of Isolating Leukocytes [PDF]
William A. Skoog, William S. Beck
openalex +1 more source
To investigate the mechanisms about the enhanced buffering effect and morphological retention in fully lithiated Sn–Bi alloys, this study introduces a new bulk bimetallic Sn–Bi alloy with fine grains of uniformly distributed Sn and Bi alloys (≈50 nm) via cooling rate control. This design effectively relieves internal energy buildup and suppresses crack
Hyeon Seo Park+6 more
wiley +1 more source
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source