Results 121 to 130 of about 933,022 (336)
Engineering of a functional protein corona with a synergistic heparin‐ATIII complex significantly improves hemocompatibility of PEG nanoparticles. Through deliberate engineering of the protein corona, a 4‐fold reduction in coagulation activation (F1 + 2) without inducing adverse thromboinflammatory reactions (CD11b, C5a) is achieved without disrupting ...
Vaidehi Londhe+5 more
wiley +1 more source
Leukocyte alkaline phosphatase activity in hematopoietic disorders.A correlative study by biochemical and cytochemical techniques [PDF]
Aaron G. Meislin+3 more
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A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li+8 more
wiley +1 more source
Mixed Agglutination of Leukocytes and Erythrocytes in Relation to Studies of Leukocyte Antigens [PDF]
Richard Bakemeier, Scott N. Swisher
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Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang+12 more
wiley +1 more source
CHANGES IN CIRCULATING LEUKOCYTES FOLLOWING THE ADMINISTRATION OF ADRENAL CORTEX EXTRACT (ACE) AND ADRENOCORTICOTROPIC HORMONE (ACTH) IN INFECTIOUS MONONUCLEOSIS AND CHRONIC LYMPHATIC LEUKEMIA [PDF]
Richard H. Saunders, Elijah Adams
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Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley +1 more source
Studies on the Genetics of Leukocyte Antigens [PDF]
Parviz Lalezari, Theodore H. Spaet
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This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah+9 more
wiley +1 more source