Results 241 to 250 of about 548,284 (288)

Relationship between Urine Protein-To-Creatinine Ratio and Leukocyte Esterase in Canine Urine Samples. [PDF]

Vet Med Sci
Liao CY, Cheng TL, Lai CH.
europepmc   +1 more source

Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat).

, 1994
Julio Herrero García, K F Liu, Yuki Yoshida, J Lian, S Chen, Gregory J. del Zoppo   +5 more
openalex   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

HPV-Driven Immune Evasion in Cervical Cancer: Transcriptomic Identification of Downregulated Hub Genes and Suppressed Leukocyte Migration Pathways. [PDF]

Int J Mol Sci
Ismael Ameen S, Masoudi M, Azizi H, Skutella T.   +3 more
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Addressing Heterogeneity in Equine PRP Therapies: A Scoping Review of Methods, Evidence, and Commercial Validation. [PDF]

Animals (Basel)
Carmona JU, López C, Argüelles D.
europepmc   +1 more source

Was the occurrence of mycoplasma pneumoniae pneumonia combined with cerebral watershed infarction a coincidence?: A CARE compliant case series and literature review. [PDF]

Medicine (Baltimore)
Wang YY, Cui JL, Mo F, Li GF.
europepmc   +1 more source

Ginsenoside Rg3-enriched red ginseng extract mitigates sepsis by inhibiting platelet-leukocyte aggregates and regulates thrombo-inflammatory pathways. [PDF]

J Ginseng Res
Lee YY, Akram AW, Saba E, Chae HK, Seo MG, Kim SD, Park SJ, Kwak D, Rhee MH.   +8 more
europepmc   +1 more source

Efficacy of Platelet-Rich Plasma Injections in Knee Osteoarthritis: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Nawaz HMT, Jawwad MA, Khan MU, Qadir MJ, Farooq MO, Nawaz MH.   +5 more
europepmc   +1 more source