Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu+5 more
wiley +1 more source
Platelet apheresis with additive solution and plasma rinseback affects the cellular composition of LRS chamber products. [PDF]
Kronenberg K+8 more
europepmc +1 more source
Single‐cell RNA sequencing identifies MMP11⁺ CAFs as pro‐angiogenic cells accumulating during bladder cancer progression. These cells promote angiogenesis by regulating ESM1⁺ tip endothelial cells and recruiting SPP1⁺ macrophages. Tumor‐derived BMP2 promotes their activation.
Wuwu Xu+13 more
wiley +1 more source
Neutrophil-to-Lymphocyte ratio as surrogate for JAK2<sup>V617F</sup> suppression and event-free survival in polycythemia vera. [PDF]
Barbui T+15 more
europepmc +1 more source
Transcriptomic profile of microglia following inflammation-sensitized hypoxic-ischemic brain injury in neonatal rats suggests strong contribution to neutrophil chemotaxis and activation. [PDF]
Bremer AS+5 more
europepmc +1 more source
Platelet-Rich Plasma in Cardiovascular Regeneration: Mechanistic Insights, Technological Innovations, and Future Directions. [PDF]
Tian J+7 more
europepmc +1 more source
Clinical subtypes identification and feature recognition of sepsis leukocyte trajectories based on machine learning. [PDF]
Miao S, Liu Y, Li M, Yan J.
europepmc +1 more source
Prostate Tissue-Induced Platelet Activation and Platelet-Neutrophil Aggregation Following Transurethral Resection of the Prostate Surgery: An In Vitro Study. [PDF]
Lin PA+7 more
europepmc +1 more source