Results 21 to 30 of about 548,284 (288)
Frontiers in Cell and Developmental Biology, 2021 Type 2 Diabetes Mellitus (T2DM) is a chronic inflammatory disorder that is characterized by chronic hyperglycemia and impaired insulin signaling which in addition to be caused by common metabolic dysregulations, have also been associated to changes in ...
Laleh Pezhman +4 more
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Nature Communications, 2020 Production of inflammatory mediators by M1-polarized macrophages is thought to rely on suppression of mitochondrial metabolism in favor of glycolysis. Refining this concept, here the authors define metabolic targets of nitric oxide as responsible for the
Erika M. Palmieri +13 more
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Postprandial Glucose Spikes, an Important Contributor to Cardiovascular Disease in Diabetes?
Frontiers in Cardiovascular Medicine, 2020 Clinical trials investigating whether glucose lowering treatment reduces the risk of CVD in diabetes have thus far yielded mixed results. However, this doesn't rule out the possibility of hyperglycemia playing a major causal role in promoting CVD or ...
Nordin M. J. Hanssen +7 more
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Genel Tıp Dergisi, 2021 Amaç: Bu çalışmada akut apandisit hastalarında ghrelin hormonunun tanısal değerininin incelenmesi ve white blood cell (WBC), c-reaktif protein (CRP) gibi rutin kullanılan laboratuvar testleriyle korelasyonunun değerlendirilmesi amaçlanmıştır.
Rıfat Peksöz +5 more
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Frontiers in Immunology, 2018 B cell expansion with NF-κB and T cell anergy (BENTA) is a rare primary immunodeficiency disorder caused by mutations in the CARD11 gene and results in constitutive NF-κB activation in B and T cells. Affected patients present with polyclonal expansion of
Maya Gupta +11 more
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Frontiers in Physiology, 2021 This study aimed to systematically review the association between telomere length (TL) and muscular fitness. In October 2020, an articles search was applied to PubMed, Scopus, and Web of Science.
Adilson Marques +13 more
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Insights Into Leukocyte Trafficking in Inflammatory Arthritis – Imaging the Joint
Frontiers in Cell and Developmental Biology, 2021 The inappropriate accumulation and activation of leukocytes is a shared pathological feature of immune-mediated inflammatory diseases (IMIDs), such as rheumatoid arthritis (RA) and psoriatic arthritis (PsA).
Julia E. Manning +3 more
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Chronic sympathetic driven hypertension promotes atherosclerosis by enhancing hematopoiesis
Haematologica, 2019 Hypertension is a major, independent risk factor for atherosclerotic cardiovascular disease. However, this pathology can arise through multiple pathways, which could influence vascular disease through distinct mechanisms.
Annas Al-Sharea +17 more
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Frontiers in Immunology, 2019 Severe combined immunodeficiency (SCID) represents one of the most severe forms of primary immunodeficiency (PID) disorders characterized by impaired cellular and humoral immune responses.
Jahnavi Aluri +18 more
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Excess Ascorbate is a Chemical Stress Agent against Proteins and Cells
Pharmaceuticals, 2020 Excess ascorbate (as expected in intravenous treatment proposed for COVID-19 management, for example) oxidizes and/or degrades hemoglobin and albumin, as evidenced by UV-vis spectroscopy, gel electrophoresis, and mass spectrometry.
Maria Lehene +7 more
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