Results 31 to 40 of about 183,293 (251)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

An Overview of The Total Leukocyte Count in Pulmonary Tuberculosis Patients at RSUD Gambiran Kediri City

Biology, Medicine & Natural Product Chemistry
The leukocyte count examination in tuberculosis infection serves to monitor the inflammation caused by Mycobacterium tuberculosis. An increasing leukocyte count can lead to complications such as pleuritis.
Devi Nor Fitri, Lisa Savitri, Rochmad Krissanjaya, Elfred Rinaldo Kasimo   +3 more
doaj   +1 more source

Changes in total and differential leukocyte counts during the clinically silent liver phase in a controlled human malaria infection in malaria-naïve Dutch volunteers

Malaria Journal, 2017
Background Both in endemic countries and in imported malaria, changes in total and differential leukocyte count during Plasmodium falciparum infection have been described.
Marlies E. van Wolfswinkel, Marijke C. C. Langenberg, Linda J. Wammes, Robert W. Sauerwein, Rob Koelewijn, Cornelus C. Hermsen, Jaap J. van Hellemond, Perry J. van Genderen   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Selection for leukocyte counts in mice

Genetical Research, 1966
By directional selection for total leukocyte counts from a hybrid mouse stock we have gradually established two lines of mice, LLC (Low Leukocyte Count) and HLC (High Leukocyte Count), which differ both in total and in differential leukocyte counts. A randombred line (RLC) is also being concurrently maintained.
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Diagnostic Value of C-Reactive Protein and Total Leukocyte Count in Acute Appendicitis

Pakistan Armed Forces Medical Journal
Objective: To find the diagnostic value of C-Reactive Protein and Total Leukocyte Count in acute appendicitis. Study Design: Validation study. Place and Duration of Study: Department of Surgery, Combined Military Hospital, Bahawalpur Pakistan, from ...
Erisha Komal, Muhammad Saeed Akhtar, Khurrum Niaz, Wasif Idris Ahmed, Muhammad Ahsan Mustafa   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study

ESC Heart Failure, 2021
Aims Platelet indices have been associated with traditional cardiovascular risk factors, cardiovascular diseases and all‐cause mortality. This study aimed to investigate the role of platelet count, mean platelet volume (MPV) and platelet‐to‐leukocyte ...
Bianca Dahlen, Andreas Schulz, Sebastian Göbel, Sven‐Oliver Tröbs, Sören Schwuchow‐Thonke, Henri M. Spronk, Jürgen H. Prochaska, Natalie Arnold, Karl J. Lackner, Tommaso Gori, Hugo tenCate, Thomas Münzel, Philipp S. Wild, Marina Panova‐Noeva   +13 more
doaj   +1 more source