Results 51 to 60 of about 190,065 (286)
Indian Journal of Dental Sciences, 2017 Background: Many systemic diseases have been implicated as risk factors in periodontal disease. Studies suggest that periodontal infection can adversely affect systemic health; by inference periodontal disease will also have an effect on blood values ...
Devinder Singh Kalsi +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Association of nutritional anemia with leukocyte and platelet counts in people of Odisha
National Journal of Physiology, Pharmacy and Pharmacology, 2018 Background: Anemia is the most common hematological disorder in the world, due to deficiency of micronutrients such as iron, Zn, Se, Cu, folic acid, and vitamins. Iron deficiency impairs immune response and bactericidal activity of macrophages, monocytes,
Priyadarsini Samanta +1 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Plasma Neutrophil Gelatinase-associated Lipocalin and Leukocyte Differential Count in Children with Febrile Urinary Tract Infection [PDF]
, 2021 Purpose We aimed to study the association of plasma neutrophil gelatinase-associated lipocalin (pNGAL) and leukocyte differential count in children with febrile urinary tract infection (UTI).
Kee Hwan Yoo, Min Hwa Son, Hyung Eun Yim
core +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Asian Journal of Medical Sciences, 2022 Background: Neonatal sepsis is a major cause of morbidity and mortality in newborn.Early diagnosis of neonatal sepsis is the top priority to all clinicians for early initiation of appropriate treatment which will reduce the morbidity and mortality in ...
Nilay Ranjan Bagchi
doaj +1 more source
Leukocyte 5-part differential count using a microfluidic cytometer
, 2011 A portable leukocyte differential count is especially desirable for the emerging needs from bedside and NASA spaceflight healthcare. However, previous efforts to miniaturize the test using microfluidics have shown only a 3-part differential of leukocyte ...
A. Fridge +9 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Effect of cancer on hemoglobin, leukocyte count and platelet count following sepsis.
, 2016 Cancer, in isolation, decreased serum hemoglobin levels (A ...
Alton B. Farris (414528) +9 more
core +1 more source