Results 141 to 150 of about 164,771 (306)
Leukocyte classification using relative-relationship-guided contrastive learning
Hematologic diseases and blood disorders can be studied through microscopic examination of blood smear images or chemical assays. Many researchers are focused on utilizing deep learning (DL) to identify, quantify, and classify various types of blood ...
Li, Zuoyong +5 more
core +1 more source
Advanced Science, EarlyView.Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li +6 more
wiley +1 more source
Advanced Science, EarlyView.Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li +13 more
wiley +1 more source
DNA Banking of Primary Immunodeficiency Disorders in Iran
Iranian Journal of Allergy, Asthma and Immunology, 2006 Primary immunodeficiency disorders are a heterogeneous group of genetic disorders, with different modes of inheritance, consisting of more than 100 different types.
"Anna Isaian +10 more
doaj
Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates
Advanced Science, EarlyView.Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao +4 more
wiley +1 more source
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source
[Human leukocyte antigen-G (HLA)-G as a biomarker in cancer]
, 2014 Human leukocyte antigen is a class I HLA classic molecule that is preferentially expressed in cytotrophoblast cells and participates in tolerance and immune system suppression. The expression of HLA-G is induced in viral infections, autoimmune disorders,
Porras-Dorantes A, García-Ortiz JE
core +1 more source
Advanced Science, EarlyView.An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang +10 more
wiley +1 more source