Results 11 to 20 of about 1,587,061 (308)

Association of maternal leukocyte, monocyte, and neutrophil counts with hypertensive disorders of pregnancy: the Japan Environment and Children’s Study (JECS) [PDF]

open access: yesScientific Reports
Hypertensive disorders of pregnancy (HDP) increase the risk of preterm births and cesarean delivery. This study aimed to investigate whether maternal blood leukocyte, monocyte, or neutrophil counts in the first trimester are related to the development of
Shiori Ishiyama   +13 more
doaj   +3 more sources

Accuracy of leukocyte alkaline phosphatase score to predict JAK2 V617F mutation [PDF]

open access: yesHaematologica, 2007
Granulocyte activation parameters have been described in patients with myeloproliferative disorders (MPD). We have evaluated the accuracy of leukocyte alkaline phosphatase (LAP) score to predict JAK2 V617F mutation.
Ana L Basquiera   +5 more
doaj   +2 more sources

Leukocyte Adhesion Deficiency Disorder in an Infant [PDF]

open access: yesInternational Journal of Immunopathology and Pharmacology, 1999
Leukocyte adhesion defect (LAD) is an inherited disorder of phagocytic function. The three different alpha-chains of the leukocyte integrin family (CD 11a, 11b, 11c) are all dependent on the common beta chain (CD18) for proper insertion into the cell membrane.
G. SABATINO   +4 more
openaire   +5 more sources

ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]

open access: yes, 1997
Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Weber, Christian   +7 more
core   +1 more source

Genetic association of leukocyte telomere length with Graves’ disease in Biobank Japan: A two-sample Mendelian randomization study

open access: yesFrontiers in Immunology, 2022
BackgroundTelomere length (TL) has been recognized to be fundamental to the risk of autoimmune disorders. However, the role of leukocyte TL in Graves’ disease has not yet been fully elucidated.
Meijie Ye, Yu Wang, Yiqiang Zhan
doaj   +1 more source

Leukocyte margination in alveolar capillaries: Interrelationship with functional capillary geometry and microhemodynamics [PDF]

open access: yes, 1999
The pulmonary capillary microvasculature harbors a large pool of intravascularly marginated leukocytes. In this study, we investigated the interrelationship of leukocyte margination with characteristics of functional capillary geometry and ...
Kuhnle, Gerhard E. H.   +5 more
core   +1 more source

In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue [PDF]

open access: yes, 2009
Directional migration of transmigrated leukocytes to the site of injury is a central event in the inflammatory response. Here, we present an in vivo chemotaxis assay enabling the visualization and quantitative analysis of subtype-specific directional ...
Alexander Georg Khandoga   +11 more
core   +2 more sources

Leukocyte Alkaline Phosphatase in Hematological Disorders

open access: yesLeukocyte Alkaline Phosphatase in Hematological Disorders
Leukocyte alkaline phosphatase activity was studied biochemically and histochemically in various blood diseases. 1) N-APA is preferable to LAPA as a unit of biochemical measurement. 2) The low content of leukocyte AP in CGL was confirmed. The determination of leukocyte AP is useful in the diagnosis and treatment of CGL. 3) The low N-APA in CGL rises to
Ozono, Noboru   +4 more
openaire   +2 more sources

Leukocyte integrins: Role in leukocyte recruitment and as therapeutic targets in inflammatory disease [PDF]

open access: yes, 2014
Infection or sterile inflammation triggers site-specific attraction of leukocytes. Leukocyte recruitment is a process comprising several steps orchestrated by adhesion molecules, chemokines, cytokines and endogenous regulatory molecules.
Vasileia I. Alexaki   +11 more
core   +1 more source

Attenuation of leukocyte sequestration by selective blockade of PECAM-1 or VCAM-1 in murine endotoxemia [PDF]

open access: yes, 2004
Background: Molecular mechanisms regulating leukocyte sequestration into the tissue during endotoxemia and/or sepsis are still poorly understood. This in vivo study investigates the biological role of murine PECAM-1 and VCAM-1 for leukocyte sequestration
Kuebler, Wolfgang M.   +4 more
core   +1 more source

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