Association of maternal leukocyte, monocyte, and neutrophil counts with hypertensive disorders of pregnancy: the Japan Environment and Children’s Study (JECS) [PDF]
Hypertensive disorders of pregnancy (HDP) increase the risk of preterm births and cesarean delivery. This study aimed to investigate whether maternal blood leukocyte, monocyte, or neutrophil counts in the first trimester are related to the development of
Shiori Ishiyama +13 more
doaj +3 more sources
Accuracy of leukocyte alkaline phosphatase score to predict JAK2 V617F mutation [PDF]
Granulocyte activation parameters have been described in patients with myeloproliferative disorders (MPD). We have evaluated the accuracy of leukocyte alkaline phosphatase (LAP) score to predict JAK2 V617F mutation.
Ana L Basquiera +5 more
doaj +2 more sources
Leukocyte Adhesion Deficiency Disorder in an Infant [PDF]
Leukocyte adhesion defect (LAD) is an inherited disorder of phagocytic function. The three different alpha-chains of the leukocyte integrin family (CD 11a, 11b, 11c) are all dependent on the common beta chain (CD18) for proper insertion into the cell membrane.
G. SABATINO +4 more
openaire +5 more sources
ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]
Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Weber, Christian +7 more
core +1 more source
BackgroundTelomere length (TL) has been recognized to be fundamental to the risk of autoimmune disorders. However, the role of leukocyte TL in Graves’ disease has not yet been fully elucidated.
Meijie Ye, Yu Wang, Yiqiang Zhan
doaj +1 more source
Leukocyte margination in alveolar capillaries: Interrelationship with functional capillary geometry and microhemodynamics [PDF]
The pulmonary capillary microvasculature harbors a large pool of intravascularly marginated leukocytes. In this study, we investigated the interrelationship of leukocyte margination with characteristics of functional capillary geometry and ...
Kuhnle, Gerhard E. H. +5 more
core +1 more source
In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue [PDF]
Directional migration of transmigrated leukocytes to the site of injury is a central event in the inflammatory response. Here, we present an in vivo chemotaxis assay enabling the visualization and quantitative analysis of subtype-specific directional ...
Alexander Georg Khandoga +11 more
core +2 more sources
Leukocyte Alkaline Phosphatase in Hematological Disorders
Leukocyte alkaline phosphatase activity was studied biochemically and histochemically in various blood diseases. 1) N-APA is preferable to LAPA as a unit of biochemical measurement. 2) The low content of leukocyte AP in CGL was confirmed. The determination of leukocyte AP is useful in the diagnosis and treatment of CGL. 3) The low N-APA in CGL rises to
Ozono, Noboru +4 more
openaire +2 more sources
Leukocyte integrins: Role in leukocyte recruitment and as therapeutic targets in inflammatory disease [PDF]
Infection or sterile inflammation triggers site-specific attraction of leukocytes. Leukocyte recruitment is a process comprising several steps orchestrated by adhesion molecules, chemokines, cytokines and endogenous regulatory molecules.
Vasileia I. Alexaki +11 more
core +1 more source
Attenuation of leukocyte sequestration by selective blockade of PECAM-1 or VCAM-1 in murine endotoxemia [PDF]
Background: Molecular mechanisms regulating leukocyte sequestration into the tissue during endotoxemia and/or sepsis are still poorly understood. This in vivo study investigates the biological role of murine PECAM-1 and VCAM-1 for leukocyte sequestration
Kuebler, Wolfgang M. +4 more
core +1 more source

