Results 21 to 30 of about 164,771 (306)

Shining a Light on Intestinal Traffic

Clinical and Developmental Immunology, 2012
Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is associated with enhanced leukocyte infiltration to the gut, which is directly linked to the clinical aspects of these disorders.
Carola T. Murphy, Kenneth Nally, Fergus Shanahan, Silvia Melgar   +3 more
doaj   +1 more source

Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation. [PDF]

, 2014
Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development of neuroinflammatory disorders ...
Susanne MA van der Pol, Male, David K, Cerutti, Camilla, Michael, G.J., Dongsheng Wu, van der Pol, SM, Sharrack, B, Romero, I.A., Baker, D., Michael, Gregory J, Simpson, Julie E., Cerutti, C., Simpson, J.E., Lopez-Ramirez, Miguel A., David Baker, Romero, IA, Wu, D.S., de Vries, H.E., Baker, David, King-Robson, J., Basil Sharrack, Simpson, Julie E, Michael, GJ, Wu, Dongsheng, van der Pol, Susanne M A, Hirst, Mark C, Julie E Simpson, Ignacio A Romero, Pryce, Gareth, Baker, D, Gregory J Michael, de Vries, Helga E, Romero, Ignacio A., Hirst, MC, King-Robson, Josh, de Vries, HE, Lopez-Ramirez, Alejandro, Mark C Hirst, David K Male, Male, DK, de Vries, Helga E., Gareth Pryce, Josh King-Robson, Camilla Cerutti, van der Pol, SMA, Romero, Ignacio A, van der Pol, S.M.A., Lopez-Ramirez, Miguel A, Male, D.K., Male, David K., Sharrack, B., King-Robson, J, van der Pol, Susanne M. A., Wu, D, Simpson, JE, Lopez-Ramirez, MA, Miguel A Lopez-Ramirez, Hirst, M.C., van der Pol, Susanne Ma, Cerutti, C, Helga E de Vries, Pryce, G, Pryce, G., Hirst, Mark C., Sharrack, Basil, Michael, Gregory J., Lopez-Ramirez, M.A.   +66 more
core   +1 more source

Platelet volume variation in major psychiatric disorders

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Mean platelet volume (MPV) is one of the indicators of platelet function. Changes in platelet function have been reported in many psychiatric disorders.
Murat Ilhan Atagun, Sukru Alperen Korkmaz, Caglar Soykan, Serdar Suleyman Can, Semra Ulusoy Kaymak, Ali Caykoylu   +5 more
doaj  

Causal relationships between telomere length and liver disease: a Mendelian randomization study

Frontiers in Genetics, 2023
Background: Leukocyte telomere length and hepatic disorders have been linked in various research studies, although their causative association has not been clarified.
Shuangjing Zhu, Mengtao Yang, Ting Wang, Zhen Ding   +3 more
doaj   +1 more source

MicroRNA-155 contributes to shear-resistant leukocyte adhesion to human brain endothelium in vitro [PDF]

, 2016
Background: Increased leukocyte adhesion to brain endothelial cells forming the blood–brain barrier (BBB) precedes extravasation into the central nervous system (CNS) in neuroinflammatory diseases such as multiple sclerosis (MS).
de Vries, H, Cerutti, Camilla, de Vries, Helga, Male, DK, Dongsheng Wu, Romero, I.A., Sharrack, B, Helga de Vries, Camilla Cerutti, Patricia Soblechero-Martin, Cerutti, C., Male, D.K., Romero, IA, David Kingsley Male, Sharrack, B., Soblechero-Martin, P., Basil Sharrack, Wu, D., Ignacio Andres Romero, Soblechero-Martin, P, Wu, Dongsheng, Lopez-Ramirez, Miguel Alejandro, Wu, D, Lopez-Ramirez, MA, Male, David Kingsley, Romero, Ignacio Andres, Miguel Alejandro Lopez-Ramirez, de Vries, H., Cerutti, C, Soblechero-Martin, Patricia, Sharrack, Basil, Lopez-Ramirez, M.A.   +31 more
core   +1 more source

Leukocyte transcriptome of Cushing’s disease are associated with nerve impairment and psychiatric disorders

, 2023
Introduction: The hypothalamus-pituitary-adrenal (HPA) axis and its end product cortisol is a major response mechanism to stress and plays a critical role in many psychiatric disorders. Cushing’s disease (CD) serves as a valuable in vivo “hyperexpression”
He, Kunyu; Department of Neurosurgery, The First Medical Centre of Chinese PLA General Hospital, Beijing, China; Chinese PLA Medical School, Beijing, China, Zhang, Yanyang; Department of Neurosurgery, The First Medical Centre of Chinese PLA General Hospital, Beijing, China, Wang, Fuyu; Department of Neurosurgery, The First Medical Centre of Chinese PLA General Hospital, Beijing, China, Zhou, Tao; Department of Neurosurgery, The First Medical Centre of Chinese PLA General Hospital, Beijing, China, Li, Fangye; Department of Neurosurgery, The First Medical Centre of Chinese PLA General Hospital, Beijing, China, Yu, Xinguang; Department of Neurosurgery, The First Medical Centre of Chinese PLA General Hospital, Beijing, China   +5 more
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Risk assessment of substance use disorders based on the human leukocyte antigen (HLA)

Scientific Reports, 2023
Substance use disorders (SUDs) are common and costly conditions that are partially attributable to genetic factors. In light of immune system influences on neural and behavioral aspects of addiction, the present study evaluated the influence of genes ...
Lisa M. James, Apostolos P. Georgopoulos
doaj   +1 more source

Leukocyte Alkaline Phosphatase in Hematological Disorders [PDF]

, 1960
Leukocyte alkaline phosphatase activity was studied biochemically and histochemically in various blood diseases. 1) N-APA is preferable to LAPA as a unit of biochemical measurement. 2) The low content of leukocyte AP in CGL was confirmed.
Ozono, Noboru, Watanabe, Bunro, Kamochi, Yasuro, Tomonaga, Masanobu, Toyoda, Shigeki   +4 more
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Novel t(5;19) Translocation in a Patient with PDGFRB Associated Chronic Leukemia: Implications for Treatment Strategy

Case Reports in Hematology, 2013
Myeloproliferative disorders are variable disorders, based on the genetic abnormality present and the cell line progenitors that are affected. In this case, we discuss a novel gene translocation in the subset of PDGFRB mutations, first seen with ...
Joel D. Provenzano, J. Phillip Kuebler
doaj   +1 more source

THE RELATIONSHIP BETWEEN BLOOD GROUPS AND PLATELETCRIT IN HEALTHY TURKISH POPULATION

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi, 2022
Objective Plateletcrit (PCT) and mean platelet volume (MPV) are important platelet indices that are associated with various systemic and inflammatory disorders.
Demircan Özbalcı, Emine Güçhan Alanoğlu, Funda Yıldırım Baş, Nur Banu Tatar, Yavuz Özcan, Hasan Yasan, Erşan Kaya   +6 more
doaj   +1 more source