Results 291 to 300 of about 248,987 (332)

Disorders of Leukocyte Chemotaxis

Pediatric Clinics of North America, 1977
The rapid accumulation of inflammatory cells at sites of microbial invasion or neoplastic transformation is a central event in immunologically-mediated host defense. The availability of methodology to accurately quantify leukocyte migration in vitro has allowed the disclosure of previously unrecognized clinical disorders, namely leukocyte dysmotility ...
R, Snyderman, M C, Pike
openaire   +2 more sources

Disorders of Polymorphonuclear Leukocyte Function

Hospital Practice, 1985
In Part II of the discussion of PMN function, the focus is on ways in which the complex biochemical processes that modulate cell motility and oxygen radical formation can go wrong. Derangements of these functions—hyperactive as well as hypoactive phagocytosis—lead to clinical disorders that predispose the host to infection and inflammatory reactions.
G J, Boxer, J T, Curnutte, L A, Boxer
openaire   +2 more sources

Leukocyte function and nonmalignant leukocyte disorders

Current Opinion in Pediatrics, 1993
This review summarizes recent literature regarding the clinical and molecular features of nonmalignant leukocyte disorders in children. Leukocyte adhesion deficiency and chronic granulomatous disease, two inherited disorders of neutrophil function, continue to be the best-characterized disorders with respect to specific molecular defects.
openaire   +2 more sources

Leukocyte Function in Chronic Myeloproliferative Disorders

Blood Cells, Molecules, and Diseases, 1998
The myeloproliferative disorders (MPD) are clonal diseases that originate from a transformed stem cell and involve all myeloid lineage. The affected cells have both proliferative and functional impairment. Therefore, we evaluated and compared neutrophil function in 31 patients with polycythemia vera (PV), idiopathic myelofibrosis (MF), chronic myeloid ...
B, Wolach, R, Gavrieli, Y, Manor, M, Lishner   +3 more
openaire   +2 more sources

Nonmalignant Disorders of Leukocytes

DeckerMed Medicine, 2011
Leukocytes, also known as white blood cells, are hematologic cells important for a host’s immune defense. They comprise several diverse cell types including lymphocytes, neutrophils, monocytes, macrophages, and eosinophils. Each plays a unique and important role in fighting infection, cancer surveillance, and maintaining immune homeostasis.
Nancy Berliner, Alison M. Schram
openaire   +1 more source

Nonmalignant Leukocyte Disorders

2016
Abnormalities of leukocyte count are routinely encountered in medical practice and rank among the most common reasons for hematologists to be consulted. The question often begins with whether there is a primary hematologic disorder, a clonal malignancy, versus a purely reactive process where the only required therapy would be directed toward the ...
Lawrence Rice, Miho Teruya
openaire   +1 more source