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Leukocyte mitochondrial DNA copy number in bipolar disorder
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2014Evidence supports the role for mitochondrial impairment in the pathophysiology of bipolar disorder (BD). BD has been associated with decreased mitochondrial electron transport chain activity and increased oxidative stress. Also, mitochondrial DNA (mtDNA) encodes mitochondrial electron transport chain proteins and has been associated with altered ...
Rafael T, de Sousa +7 more
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WHIM syndrome: a genetic disorder of leukocyte trafficking
Current Opinion in Allergy and Clinical Immunology, 2003WHIM syndrome (the association of warts, hypogammaglobulinemia, recurrent bacterial infections, and 'myelokathexis') is a rare congenital form of neutropenia associated with an unusual immune disorder involving hypogammaglonulinemia and abnormal susceptibility to warts.
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Altered arachidonate metabolism by leukocytes and platelets in myeloproliferative disorders
Prostaglandins, Leukotrienes and Medicine, 1983The arachidonate metabolism by leukocytes and platelets was studied in 14 patients with myeloproliferative disorders including 7 patients with chronic myeloid leukemia (CML), 5 with polycythemia vera (PV) and 2 with essential thrombocythemia (ET).
H, Takayama +5 more
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[Glycosaminoglycans in leukocytes in myeloproliferative disorders].
Voprosy meditsinskoi khimii, 1984Content and composition of glycosaminoglycans (GAG) was studied in leukocytes of 30 healthy persons and of patients with different types of myeloproliferative disorders: 32 patients with chronic myeloid leukemia (CML), 10 patients with polycythemia vera (PV), 5 patients with idiopathic myeloid fibrosis (IMF) and 10 patients with acute myelo blast ...
M F, Kharchenko +4 more
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[Disorders in leukocyte function in diabetes mellitus].
Schweizerische medizinische Wochenschrift, 1978A group of diabetic patients have been analyzed with regard to their defense against infection, i.e. chemotaxis, phagocytosis and bacterial killing. All three steps of leukocyte function are deteriorated in diabetes mellitus. However, no definitive statement on defense against infection can at present be made.
A F, Viollier, H J, Senn
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