Results 261 to 270 of about 1,587,061 (308)

Deletion of leukocyte mitochondrial DNA in bipolar disorder

Journal of Affective Disorders, 1996
Leukocyte mitochondrial DNA (mtDNA) was examined in 35 patients with bipolar disorder by the nested PCR method to explore whether or not the 4977 base-pair deletion (common deletion) is found. The PCR product corresponding to the common deletion was found in 2 of 35 (5.7%) patients and none of 29 normal controls.
T, Kato, Y, Takahashi
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Physiological Roles of Leukocytes and Disorders

2018
This chapter describes white blood cells of the peripheral blood: neutrophils, eosinophils, basophils, monocytes, and lymphocyte subsets. It describes their basic physiology and important disease states associated with defects of each of these entities. Each of these cells arises from a common bone marrow myeloid or lymphoid progenitor to differentiate
Jahnavi Gollamudi, Alex Y. Huang, Evi X. Stavrou   +2 more
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Leukocyte telomerase activity and antidepressant efficacy in bipolar disorder

European Neuropsychopharmacology, 2014
Telomeres are DNA-protein complexes that cap linear DNA strands, protecting DNA from damage. Recently, shorten telomeres length has been reported in bipolar disorder (BD) and depression. The enzyme telomerase regulates telomeres׳ length, which has been associated with cellular viability; however it is not clear how telomerase may be involved in the ...
Marcio Gerhardt, Soeiro-de-Souza, Antonio L, Teixeira, Elvis C, Mateo, Marcus V, Zanetti, Flavia G, Rodrigues, Vanessa J, de Paula, Julia F, Bezerra, Ricardo A, Moreno, Wagner F, Gattaz, Rodrigo, Machado-Vieira   +9 more
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Leukocyte mitochondrial DNA copy number in bipolar disorder

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2014
Evidence supports the role for mitochondrial impairment in the pathophysiology of bipolar disorder (BD). BD has been associated with decreased mitochondrial electron transport chain activity and increased oxidative stress. Also, mitochondrial DNA (mtDNA) encodes mitochondrial electron transport chain proteins and has been associated with altered ...
Rafael T, de Sousa, Miyuki, Uno, Marcus V, Zanetti, Sueli M O, Shinjo, Geraldo F, Busatto, Wagner F, Gattaz, Sueli K N, Marie, Rodrigo, Machado-Vieira   +7 more
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Cyclic-AMP production by polymorphonuclear leukocytes in psychiatric disorders

Biological Psychiatry, 1989
The cyclic adenosine monophosphate (cAMP) responses to histamine, prostaglandin-E1, and isoproterenol in polymorphonuclear leukocytes from drug-free normal controls and patients with schizophrenia or major depressive disorder were compared. These three groups of subjects did not differ in their cAMP responses to receptor activation.
P D, Kanof, E F, Coccaro, C A, Johns, M, Davidson, L J, Siever, K L, Davis   +5 more
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Human Leukocyte Antigen Type and Posttransplant Lymphoproliferative Disorder

Transplantation, 2015
Posttransplant lymphoproliferative disorder (PTLD) is an infrequent but serious complication of solid organ transplantation. Early detection and initiation of therapy may improve outcomes. The purpose of this study was to identify human leukocyte antigen (HLA) type as risk and prognostic factors for PTLD.A review was undertaken to identify PTLD cases ...
Mark E, Lustberg, Ronald P, Pelletier, Pierluigi, Porcu, Stanley I, Martin, Carl D, Quinion, Susan M, Geyer, Michael A, Caligiuri, Robert A, Baiocchi   +7 more
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Altered arachidonate metabolism by leukocytes and platelets in myeloproliferative disorders

Prostaglandins, Leukotrienes and Medicine, 1983
The arachidonate metabolism by leukocytes and platelets was studied in 14 patients with myeloproliferative disorders including 7 patients with chronic myeloid leukemia (CML), 5 with polycythemia vera (PV) and 2 with essential thrombocythemia (ET).
H, Takayama, M, Okuma, K, Kanaji, T, Sugiyama, S, Sensaki, H, Uchino   +5 more
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WHIM syndrome: a genetic disorder of leukocyte trafficking

Current Opinion in Allergy and Clinical Immunology, 2003
WHIM syndrome (the association of warts, hypogammaglobulinemia, recurrent bacterial infections, and 'myelokathexis') is a rare congenital form of neutropenia associated with an unusual immune disorder involving hypogammaglonulinemia and abnormal susceptibility to warts.
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[Glycosaminoglycans in leukocytes in myeloproliferative disorders].

Voprosy meditsinskoi khimii, 1984
Content and composition of glycosaminoglycans (GAG) was studied in leukocytes of 30 healthy persons and of patients with different types of myeloproliferative disorders: 32 patients with chronic myeloid leukemia (CML), 10 patients with polycythemia vera (PV), 5 patients with idiopathic myeloid fibrosis (IMF) and 10 patients with acute myelo blast ...
M F, Kharchenko, T L, Shatskaia, S S, Ostroumova, L P, Rybakova, E G, Shcherbakova   +4 more
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[Disorders in leukocyte function in diabetes mellitus].

Schweizerische medizinische Wochenschrift, 1978
A group of diabetic patients have been analyzed with regard to their defense against infection, i.e. chemotaxis, phagocytosis and bacterial killing. All three steps of leukocyte function are deteriorated in diabetes mellitus. However, no definitive statement on defense against infection can at present be made.
A F, Viollier, H J, Senn
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