Results 331 to 340 of about 237,141 (361)
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Disorders of Polymorphonuclear Leukocyte Function
Hospital Practice, 1985In Part II of the discussion of PMN function, the focus is on ways in which the complex biochemical processes that modulate cell motility and oxygen radical formation can go wrong. Derangements of these functions—hyperactive as well as hypoactive phagocytosis—lead to clinical disorders that predispose the host to infection and inflammatory reactions.
Grace Jordison Boxer +2 more
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Leukocyte function and nonmalignant leukocyte disorders
Current Opinion in Pediatrics, 1993This review summarizes recent literature regarding the clinical and molecular features of nonmalignant leukocyte disorders in children. Leukocyte adhesion deficiency and chronic granulomatous disease, two inherited disorders of neutrophil function, continue to be the best-characterized disorders with respect to specific molecular defects.
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Clinical Disorders of Leukocyte Functions [PDF]
, 1984 After being questioned by a colleague about my current endeavors with a large number of reprints, reference printouts, and writing pads apparent, I informed him that I was writing another review on clinical abnormalities of phagocyte function. Why write another such review, I was asked, as there are a number of these in the current literature (Gallin ...
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Leukocyte Function in Chronic Myeloproliferative Disorders
Blood Cells, Molecules, and Diseases, 1998The myeloproliferative disorders (MPD) are clonal diseases that originate from a transformed stem cell and involve all myeloid lineage. The affected cells have both proliferative and functional impairment. Therefore, we evaluated and compared neutrophil function in 31 patients with polycythemia vera (PV), idiopathic myelofibrosis (MF), chronic myeloid ...
Baruch Wolach +3 more
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Leukocyte-Related Disorders: A Review for the Pediatrician
Pediatric Annals, 2020Leukocytes, or white blood cells, are part of the innate immune system that defends against infectious and foreign agents. In pediatrics, it is important to use age-specific laboratory values when interpreting results. Infections are the most common cause of leukocytosis or leukopenia in children.
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Leukocyte Disorders: Quantitative and Qualitative Disorders of the Neutrophil, Part 1
Pediatrics In Review, 1996Introduction Neutrophils form the first line of defense against most bacterial and fungal pathogens after disruption of the skin and mucous membranes. Once tissue is invaded by microorganisms, a variety of vasoactive and chemotactic mediators are released by the involved tissue.
Laurence A. Boxer, R. A. Blackwood
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Nonmalignant Leukocyte Disorders
2016Abnormalities of leukocyte count are routinely encountered in medical practice and rank among the most common reasons for hematologists to be consulted. The question often begins with whether there is a primary hematologic disorder, a clonal malignancy, versus a purely reactive process where the only required therapy would be directed toward the ...
Miho Teruya +2 more
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Retinal Blood Velocity in Patients With Leukocyte Disorders
Archives of Ophthalmology, 1988The blue light entoptic phenomenon was used to measure retinal blood velocity in eight patients with chronic granulocytic leukemia, six patients with leukopenia, and matched control subjects. The retinal leukocyte velocity of the leukemic patients was 0.53 +/- 0.26 (mean +/- SD) mm/s, whereas that of the matched control subjects was 0.46 +/- 0.14 mm/s.
Timothy Rimmer +2 more
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Deletion of leukocyte mitochondrial DNA in bipolar disorder
Journal of Affective Disorders, 1996Leukocyte mitochondrial DNA (mtDNA) was examined in 35 patients with bipolar disorder by the nested PCR method to explore whether or not the 4977 base-pair deletion (common deletion) is found. The PCR product corresponding to the common deletion was found in 2 of 35 (5.7%) patients and none of 29 normal controls.
Tadafumi Kato, Yoshinari Takahashi
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Disorders of Leukocytes Leading to Recurrent Infection
Pediatric Clinics of North America, 1972Because they possess the unique property of phagocytosis, certain blood cells appear to be primarily responsible for host defense against pyogenic and fungal infection. The primary phagocyte of the peripheral blood is the polymorphonuclear neutrophil; its functions and their disorders are described in this paper.
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