Results 81 to 90 of about 1,587,061 (308)

Protective effect of fasudil, a Rho-kinase inhibitor, on chemokine expression, leukocyte recruitment, and hepatocellular apoptosis in septic liver injury.

, 2006
Rho-kinase signaling regulates important features of inflammatory reactions. Herein, we investigated the effect and mechanisms of action of the Rho-kinase inhibitor fasudil in endotoxemic liver injury.
Wang, Yusheng, Thorlacius, Henrik,, Slotta, Jan E, Thorlacius, Henrik, Thorlacius, Karin,, Menger, Michael D, Jeppsson, Bengt, Wang, Yusheng,, Laschke, Matthias W, Thorlacius, Karin, Lund University., Jeppsson, Bengt,   +11 more
core   +1 more source

Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting [PDF]

, 2007
Background: An elevated preoperative white blood cell count has been associated with a worse outcome after coronary artery bypass grafting (CABG). Leukocyte subtypes, and particularly the neutrophil-lymphocyte (N/L) ratio, may however, convey superior ...
Small, Gary R., Gibson, George, Jeffrey, Robert R., Croal, Bernard L., Gibson, Patrick H., Cuthbertson, Brian, El-Shafei, Hussein, Hillis, Graham S., Ifezulike, Ada I., Buchan, Keith G.   +9 more
core   +1 more source

Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases

Frontiers in Immunology, 2019
Tyrosine kinases relay signals from diverse leukocyte antigen receptors, innate immune receptors, and cytokine receptors, and therefore mediate the recruitment and activation of various leukocyte populations. Non-receptor tyrosine kinases of the Jak, Src,
Kata P. Szilveszter, Tamás Németh, Attila Mócsai   +2 more
doaj   +1 more source

Particle‐Level ZrO2 Atomic Layer Deposition Enables Fast‐Cycling and Long‐Life Graphite Cathodes for Dual‐Ion Batteries

Advanced Functional Materials, EarlyView.
A spatial location of atomic layer deposition (ALD)‐derived ZrO2 coatings is demonstrated to be a critical design parameter for stabilizing graphite cathodes in DIBs. Direct particle‐level ALD (PALD) screening of representative metal oxides identified ZrO2 as the coating that provides the most favorable balance of high‐rate capability and interfacial ...
Jieun Kang, Sung Eun Jo, Yunah Ji, Dongjoo Kim, Sungho Kim, Jaegeon Ryu, Jihwan An, Soojin Park   +7 more
wiley   +1 more source

Is the telomere length associated with neurocognitive disabilities in HIV-1-infected subjects?

Revista do Instituto de Medicina Tropical de São Paulo, 2018
Objective: We evaluated the association between cognitive deficits and leukocyte telomere length (LTL) in HIV-1-infected individuals. Design: 73 HIV-1-infected patients undergoing neuropsychological evaluation and 91 healthy controls were included in ...
Marilia Ladeira de Araújo, Wellington Duarte, Augusto César Penalva de Oliveira, Maria Rita Polo Gascón, Luiz Augusto Marcondes Fonseca, Raquel de Melo Alves Paiva, Bárbara Santana, Rodrigo Tocantins Calado, Jorge Casseb   +8 more
doaj   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

The role of JAM-A and PECAM-1 in modulating leukocyte infiltration in inflamed and ischemic tissues

, 2006
Innate and adaptive immunological responses are accompanied by leakocyte adhesion to the blood-vessel wall and their subsequent infiltration into the underlying tissues. In the majority of the cases, leukocytes cross the endothelium. by squeezing through
S. Nourshargh, E. Dejana, F. Krombach
core   +1 more source

Leukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio)

, 2022
Despite well-known systemic immune reactions in peripheral trauma, little is known about their roles in posttraumatic neurological disorders, such as anxiety, sickness, and cognitive impairment.
Wong, Gordon Tin-Chun, Ma, Alvin Chun-Hang, Yi, Zhen Ni, Chen, Xiang-Ke, Yi, Zhen-Ni, Kwan, Joseph Shiu Kwong, Wong, Gordon Tin Chun, Ma, Alvin Chun Hang, Chen, Xiang Ke, Kwan, Joseph Shiu-Kwong, Chang, Raymond Chuen-Chung, Chang, Raymond Chuen Chung   +11 more
core   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Vascular inflammation in central nervous system diseases: adhesion receptors controlling leukocyte-endothelial interactions [PDF]

, 2010
Leukocyte trafficking from the blood into the tissues represents a key process during inflammation and requires multiple steps mediated by adhesion molecules and chemoattractants. Inflammation has a detrimental role in several diseases, and in such cases,
Gabriela Constantin, Barbara Rossi, Stefano Angiari, ANGIARI, Stefano, Elena Zenaro, ROSSI, Barbara, CONSTANTIN, Gabriela, ZENARO, Elena, Simona Luciana Budui, BUDUI, Simona Luciana   +9 more
core   +1 more source