Results 91 to 100 of about 1,587,061 (308)

Editorial: NK cell defects: diagnosis and treatment

Frontiers in Immunology, 2023
Snehal Shabrish, Snehal Shabrish, Shanmuganathan Chandrakasan, Manisha Madkaikar   +3 more
doaj   +1 more source

Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles

Journal of Immunology Research, 2016
Extracellular vesicles (EVs) have a demonstrated involvement in modulating the immune system. It has been proposed that EVs could be used as biomarkers for detection of inflammatory and immunological disorders.
Lotte Hatting Pugholm, Rikke Bæk, Evo Kristina Lindersson Søndergaard, Anne Louise Schacht Revenfeld, Malene Møller Jørgensen, Kim Varming   +5 more
doaj   +1 more source

Nonlocomotory Robotic Strategies for Dynamic Rotation Control in Terrestrial Robots: A Review

Advanced Robotics Research, EarlyView.
Terrestrial robots increasingly require rapid body rotation to maintain stability and agility in complex environments. This review shows nonlocomotory rotational control strategies that operate without ground contact, including reaction wheels, tails, bars, limbs, and thrusters.
Y. Liang, J. An, X. Zheng, D. Wang, S. Wang, X. Wang, P. Zhu, J. Pei, S. Li, J. Paripurana, Y. Han, Z. Tang, X. Gan, Q. He, X. Ma   +14 more
wiley   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

Advanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo, Nuria Matesanz, Jorge‐Luis Torres, Alba C. Arcones, Juan Ignacio Jiménez‐Loygorri, Alfonso Mora, Leticia Herrera‐Melle, Luis Leiva‐Vega, Maria Elena Rodriguez, Lourdes Hernández‐Cosido, Marta Leon, Paula Yong González, Teresa Durán, Tamara Parracho, Francisca Mulero, Rubén Nogueiras, J. Simon C. Arthur, Angel R. Nebreda, Roger J. Davis, Miguel Marcos, Guadalupe Sabio   +20 more
wiley   +1 more source

Genetics of sleep disorders

, 2015
Sleep disorders are, in part, attributable to genetic variability across individuals. There has been considerable progress in understanding the role of genes for some sleep disorders, such as the identification of a human leukocyte antigen gene for ...
Keenan, Brendan T., Pack, Allan I., Byrne, Enda M., Gehrman, Philip R.   +3 more
core   +1 more source

Investigation into the role of annexin 1 in the microcirculation of annexin 1 knockout mice [PDF]

, 2005
PhDGlucocorticoids are used therapeutically for their anti-inflammatory and immunosuppressive actions. One of the ways they produce their potent effects is via regulation of the anti-inflammatory protein Annexin I (ANX-AI; 37 kDa protein).
Chatterjee, Bristi Emma
core   +2 more sources

Prevalence of vaginal microecological disorder and its association with HPV infections in pregnant women attending prenatal examinations

Microbiology Spectrum
Vaginal infections are closely associated with human papillomavirus (HPV) infection, yet research on vaginal microecology and HPV mRNA expression in pregnant women remains limited.
Jun Shen, Liying Wang, Wenyu Lin, Dingjie Wang, Liang Wang, Jiancui Chen, Pengming Sun   +6 more
doaj   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Leukocyte recruitment in preterm and term infants [PDF]

, 2016
Impaired cellular innate immune defense accounts for susceptibility to sepsis and its high morbidity and mortality in preterm infants. Leukocyte recruitment is an integral part of the cellular immune response and follows a well-defined cascade of events ...
Frommhold, David, Hudalla, Hannes, Katinka Karenberg, Karenberg, Katinka, Hannes Hudalla, David Frommhold   +5 more
core   +2 more sources

Trace Amine-Associated Receptors as Novel Therapeutic Targets for Immunomodulatory Disorders

Frontiers in Pharmacology, 2018
Trace amines and their receptors (trace amine-associated receptors; TAARs) are an emerging pharmacological target for the treatment of human disorders.
Sherri L. Christian, Mark D. Berry
doaj   +1 more source