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Alpha-defensin does not provide additional benefit over leukocyte esterase in the diagnosis of periprosthetic joint infection

Expert Review of Molecular Diagnostics, 2021
Background: Leukocyte esterase (LE) and α-defensin (AD) are two synovial biomarkers that are used for the diagnosis of periprosthetic joint infection (PJI), however, the superiority of one over the other remains unknown.
N. Shohat   +5 more
semanticscholar   +1 more source

Quantitative urinary tract infection diagnosis of leukocyte esterase with a microfluidic paper-based device.

Dalton Transactions, 2021
Leukocyte esterase (LE) is a useful marker that can be used in establishing a diagnosis of urinary tract infections (UTIs). The development of a UTI diagnostic method with quantitative determinations of biomarkers across all age groups is becoming more ...
W. Tseng   +7 more
semanticscholar   +1 more source

Clinical predictive value of the urine leukocyte esterase test positivity in childhood

Pediatrics International, 2021
False negative or positive results may occur in the urine dipstick test for leukocyte esterase (LE), which is used to determine urinary tract infection (UTI).
D. P. Yavas   +3 more
semanticscholar   +1 more source

Synovial fluid analysis with leukocyte esterase reagent strip test

Clinical Rheumatology, 2021
To determine whether leukocyte esterase reagent strip test (LERST) analysis could help distinguish inflammatory arthritis from mechanical joint effusion. We analyzed synovial fluid (SF) from consecutive patients with a non-traumatic joint effusion during a 6-month period. Inflammatory SF was defined by white blood cell (WBC) count ≥ 2000/mm3. The LERST
Sarah Khaleche   +5 more
openaire   +2 more sources

Chromogenic Lactate−Leukocyte Esterase Substrates

Bioconjugate Chemistry, 1997
The first successful reported use of lactate-based chromogenic, colorimetric substrates for a serine protease-based enzyme is described. A series of hydroxy-protected 5-phenyl-3-hydroxypyrrolyl L-lactate substrates of the general formula RO-Lac-OPP were prepared and formulated into reagents for the determination of leukocytes in dry phase formats.
G M, Johnson, R, Schaeper
openaire   +2 more sources

Genetic polymorphism of esterase B3 in human leukocytes

Annals of Human Genetics, 1986
SummaryHuman tissues contain an esterase activity called ESB3, detectable by starch gel electrophoresis followed by staining with α‐naphthyl butyrate. Using mononuclear leukocytes, we demonstrated an electrophoretic variant of ESB3. Family studies suggest that the variant is inherited as a simple Mendelian trait; individuals with the ESB3 2‐1 phenotype
P M, Coates, J A, Cortner
openaire   +2 more sources

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