Results 121 to 130 of about 95,034 (300)

De novo pathogenic CSF1R variant implicates microglial dysfunction in pathogenesis of febrile infection‐related epilepsy syndrome

open access: yesEpilepsia, EarlyView.
Abstract Febrile infection‐related epilepsy syndrome (FIRES) is a rare presentation of refractory status epilepticus following a febrile illness with resulting refractory epilepsy. Evidence supports the presence of immune dysregulation in patients with FIRES, but a monogenic basis for FIRES has not been identified in most cases.
Kristen S. Fisher   +9 more
wiley   +1 more source

The Application of Artificial Intelligence‐Based Bone Marrow Cell Analysis System in Pediatric Hematological Diseases

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The clinical diagnosis of hematological diseases depends on the differential count of nucleated cells on the bone marrow (BM) smears, and an artificial intelligence (AI)‐based system was applied to automatically classify BM nucleated cells in pediatric hematological disease samples in this study.
Xin He   +6 more
wiley   +1 more source

Effective treatment of advanced lung adenocarcinoma with paraneoplastic leukemoid reaction with Lorlatinib: a case report

open access: yesFrontiers in Oncology
BackgroundLorlatinib is a new generation ALK kinase inhibitor. We describe a 52-year-old patient with ALK-positive advanced lung adenocarcinoma who achieved remission after multi-line therapy combined with paraneoplastic leukemoid reaction treated with ...
Ruiqi Niu   +5 more
doaj   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova   +2 more
wiley   +1 more source

Renal Infarct After Endovascular Abdominal Aortic Aneurysm Repair: Consider in Back Pain Differential [PDF]

open access: yes, 2020
As hypertension, obesity, and hyperlipidemia become more widespread, the prevalence of abdominal aortic aneurysms (AAA) has also increased.1 Traditionally those with multiple comorbidities – also those with greatest AAA mortality – were considered too ...
Hackett, Anthony, Liu, Sophia Y.
core  

A comparative vignette study: Evaluating the potential role of a generative AI model in enhancing clinical decision‐making in nursing

open access: yesJournal of Advanced Nursing, EarlyView.
Abstract Aim This study explores the potential of a generative artificial intelligence tool (ChatGPT) as clinical support for nurses. Specifically, we aim to assess whether ChatGPT can demonstrate clinical decision‐making equivalent to that of expert nurses and novice nursing students.
Mor Saban, Ilana Dubovi
wiley   +1 more source

Gaucher disease, state of the art and perspectives

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Knowledge about Gaucher disease (GD), considered a model for rare diseases, has considerably increased since its discovery. The pathophysiology of this lysosomal disorder is better known, and specific therapies that can control many aspects of the disease have been developed, particularly for the most common form, Type 1 GD.
Fabrice Camou, Marc G. Berger
wiley   +1 more source

The incidence and risk factors of intraoperative bacterial contamination in primary total knee arthroplasty

open access: yesFrontiers in Surgery
BackgroundInfection is a devasting complication after arthroplasty. Identifying potential sources contributing to intraoperative bacterial transmission can help to reduce surgical-site infections.ObjectiveThe aim of this study was to identify the ...
Lijun Xing   +5 more
doaj   +1 more source

Malignant histiocytosis in a patient presenting with leukocytosis, eosinophilia, and lymph node granuloma [PDF]

open access: bronze, 1975
James O. Ballard   +3 more
openalex   +1 more source

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