Results 121 to 130 of about 92,663 (282)
ABSTRACT This work describes, to our knowledge, the first reported case of a patient with an MDS/MPN overlap syndrome harboring a novel KRAS::ETNK1 fusion transcript. The disease initially presented with eosinophilia, megakaryocyte expansion, mast cell infiltration, and a background of typical MDS/MPN‐associated mutations (ASXL1, TET2, EZH2, BCOR, and ...
Marianne Caledec +17 more
wiley +1 more source
Although it is known that corticosteroid administration causes leukocytosis, the magnitude and length of time this leukocytosis persists is unknown during pregnancy.
Melissa E. Bauer +5 more
core +1 more source
Emergencies in Amyotrophic Lateral Sclerosis
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal +9 more
wiley +1 more source
Abstract Background Central nervous system (CNS) involvement associated with Richter transformation (RT) is a rare complication of chronic lymphocytic leukemia (CLL). Neurological manifestations are heterogeneous. To our knowledge, no previous reports have described CNS RT presenting predominantly with psychiatric and behavioral symptoms.
Tetsuro Ishida, Yusuke Sugama
wiley +1 more source
Endotoxins and Biological Implications—Review
Graphical overview of endotoxin sources, exposure routes, biological effects, detection methods, and routes of elimination. ABSTRACT Endotoxins, also known as lipopolysaccharides (LPSs), are structural components of the outer membrane of Gram‐negative bacteria and some cyanobacteria.
Uzair Ishtiaq +5 more
wiley +1 more source
A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy
PIP5K1C‐related lethal congenital contracture syndrome with hyperinsulinism and optic atrophy. ABSTRACT Lethal congenital contracture syndrome 3 (LCCS3, MIM #611369) is a rare autosomal recessive neuromuscular disorder caused by biallelic loss‐of‐function (LOF) variants in PIP5K1C, reported in only two families to date.
Tameemi Abdalla Moady +3 more
wiley +1 more source
Background and Objectives: Search for inexpensive laboratory markers have identified associations between blood counts and lung cancer outcomes. In this study, we evaluated the prognostic value of paraneoplastic leukocytosis (p-Leukocytosis) and ...
Dana VILLLINES +2 more
core +1 more source
ABSTRACT Adult‐onset Still's disease (AOSD) is an auto inflammatory disorder with a variable clinical presentation, and without a pathognomonic diagnostic test, characterized by high spiking fever, arthralgia/arthritis, a suggestive skin rash, elevated white blood cell count 10 G/L (> 80% neutrophils), elevated ferritin, with glycosylated ferritin < 20%
M. Nordmann +7 more
wiley +1 more source
Determinants of survival in patients treated with CPX-351 for acute myeloid leukemia
CPX-351 for the treatment of acute myeloid leukemia (AML) has demonstrated better efficacy compared with standard chemotherapy regimens, with an excellent safety profile.
Patrizia Chiusolo +10 more
doaj +1 more source

