Results 141 to 150 of about 10,390 (175)

Progressive multifocal leukoencephalopathy and natalizumab

Journal of Neurology, 2011
Natalizumab (TYSABRI(®)), a specific α4-integrin antagonist, is approved as a second-line treatment of relapsing-remitting MS (RRMS) patients who fail therapy with interferons or as first-line treatment of patients with highly active relapsing-remitting disease. Since the market introduction of natalizumab as a monotherapy in July of 2006, 111 cases of
Kerstin, Hellwig, Ralf, Gold
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Natalizumab and Progressive Multifocal Leukoencephalopathy

New England Journal of Medicine, 2005
The Brief Reports on natalizumab were referred to Biogen Idec, the manufacturer, which offers the following response: After learning of one confirmed and one suspected case of progressive multifocal leukoencephalopathy (PML) in patients treated with natalizumab, Biogen Idec and Elan quickly notified the Food and Drug Administration (FDA) and other ...
Burt, Adelman, Alfred, Sandrock, Michael A, Panzara   +2 more
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Progressive Multifocal Leukoencephalopathy

New England Journal of Medicine, 1961
IN the course of the regular post-mortem examination of the brains of patients coming to autopsy at the Massachusetts General Hospital, my attention has been called in recent years to an unusual disorder of the cerebral white matter with distinctive features unfamiliar to me and my colleagues from our own experience or that of others.
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Progressive Multifocal Leukoencephalopathy in AIDS

AIDS Patient Care, 1991
CASE PRESENTATION —John Williams, MD A 42-YEAR-OLD bisexual, white man presented complaining of progressive memory loss, confusion, and difficulty speaking for 1 week. The patient had been diagnosed with acquired immunodeficiency syndrome (AIDS) a year earlier when he developed cutaneous Kaposi's sarcoma.
R E, Chaisson, D E, Griffin
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Progressive multifocal leukoencephalopathy in HIV

International Journal of STD and AIDS, 1997
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by infection of oligodendrocytes by JC virus. As patients with HIV survive longer with severe immunodeficiency, the incidence of PML is rising.
M, Sadler, M R, Nelson
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The EEG in progressive multifocal leukoencephalopathy

Electroencephalography and Clinical Neurophysiology, 1969
Abstract One original case and two previously reported cases of progressive multifocal leukoencephalopathy (PML) are reviewed, with emphasis on their EEG features. In one the diagnosis could be made and confirmed by brain biopsy prior to death. The EEG findings in these three cases and those in other cases reported in the literature suggest the value
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Progressive Multifocal Leukoencephalopathy

Journal of Computer Assisted Tomography, 1995
A case of progressive multifocal leukoencephalopathy (PML) with a classic clinical presentation but with unusual pathological and radiographic findings is reported. The pathology revealed evidence of prior hemorrhage, and imaging studies revealed focal cerebral atrophy as well as contrast enhancement on MR scans.
S, Ng, V C, Tse, J, Rubinstein, E, Bradford, D R, Enzmann, F K, Conley   +5 more
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Progressive Multifocal Leukoencephalopathy

Archives of Ophthalmology, 1977
A patient had been treated for chronic lymphocytic leukemia for five years before developing visual blurring as the manifestation of occipital lobe lesions of progressive multifocal leukoencephalopathy (PML). The disease is caused by an infection of the CNS oligodendrocytes by a papovavirus, whose replication is facilitated by an impairment of the host'
R E, Appen, H, Roth, G M, ZuRhein, J N, Varakis   +3 more
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Progressive Multifocal Leukoencephalopathy: A Case Study

Progress in Transplantation, 2007
Progressive multifocal leukoencephalopathy is a rare, highly fatal demyelinating brain infection caused by the JC virus. This infection is associated with immunosuppressive agents and is emerging in the transplant population. There has never been a documented case of progressive multifocal leukoencephalopathy in a transplant recipient receiving ...
Vicki, McCalmont, Kristi, Bennett
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PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

Acta Pathologica Japonica, 1981
Mechanism of demyelination in progressive multifocal leukoencephalopathy (PML) was elucidated by demonstrating ultrastructurally the relationship between the affected glial cells and myelin sheaths. The myelinating cells in the central nervous system, namely ollgodendroglias, were specifically attacked by PML‐virus, with eventual primary destruction of
K, Nagashima, K, Yamaguchi, K, Yasui, H, Ogiwara   +3 more
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