Results 151 to 160 of about 23,690 (177)

LEUKOENCEPHALOPATHIES AND LEUKODYSTROPHIES

Continuum, 2010
The leukoencephalopathies encompass a heterogeneous group of disorders that involve the brain white matter. The cause may be acquired or inherited; in the latter case, mutations have been found in genes that encode protein components of the myelin membrane or enzymes implicated in the turnover of myelin. In patients with cognitive dysfunction and white
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Progressive Multifocal Leukoencephalopathy

Archives of Ophthalmology, 1959
Astrom, Mancall, and Richardson1have recently directed attention to progressive multifocal leukoencephalopathy, a previously unrecognized neuropathological entity. Visual symptoms have been prominent in this disorder. As no cases have been reported in the ophthalmologic literature, the following instance of progressive multifocal leukoencephalopathy ...
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Progressive Multifocal Leukoencephalopathy

Radiology, 1976
The radionuclide, radiographic and pathologic findings in a patient with progressive multifocal leukoencephalopathy were correlated. Radionuclide imaging demonstrated the largest two of the many lesions observed at pathology. On repeated studies, one of the lesions developed a "doughnut" sign due to central necrosis. Cerebral angiography disclosed only
J, Kirsh, L, Rosenthall, M H, Finlayson, R, Wee   +3 more
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Progressive multifocal leukoencephalopathy

Current Infectious Disease Reports, 2001
Progressive multifocal leukoencephalopathy is a subacute demyelinating disease that occurs in patients with defects in cell-mediated immunity, including those with AIDS and lymphoproliferative disorders. It is caused by reactivation of JC virus (JCV), which infects 70% to 90% of the population by adulthood, but remains latent in normal hosts.
Anna R., Thorner, Joel T., Katz
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Progressive Multifocal Leukoencephalopathy

European Neurology, 1971
The present paper reports on a case of progressive multifocal leukoencephalopathy, with certain particularities.
C, Arseni, F, Nerean tiu
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Pediatric inflammatory leukoencephalopathies

Acquired demyelinating syndromes (ADS) represent acute neurologic illnesses characterized by deficits persisting for at least 24hours and involving the optic nerve, brain, or spinal cord, associated with regional areas of increased signal on T2-weighted images.
Omar, Abdel-Mannan, Yael, Hacohen
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Inherited Leukoencephalopathiesa

Seminars in Neurology, 2012
Abstract Leukoencephalopathies are disorders that selectively involve the white matter of the brain. Acquired causes of leukoencephalopathy include inflammatory, infectious, vascular, neoplastic, and toxic disorders. Hereditary leukoencephalopathies encompass conditions characterized by progressive destruction or loss of previously ...
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Leukoencephalopathies in Adulthood

Seminars in Neurology, 2012
The understanding of the genetic basis of late-onset leukoencephalopathies has continued to increase in recent years. The most commonly presenting leukoencephalopathies in adulthood can be late-onset manifestations of metabolic pathways.
Jan-Mendelt, Tillema, Deborah L, Renaud
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Acquired perinatal leukoencephalopathy

Annals of Neurology, 1984
AbstractBetween 36 and 44 weeks after conception, telencephalic white matter in the newborn appears to be particularly vulnerable to insults that result in morphological disturbances. Available evidence indicates that this disorder (or group of disorders), named acquired perinatal leukoencephalopathy, reflects a decrease in blood flow through the ...
A, Leviton, F H, Gilles
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Intracarotid BCNU leukoencephalopathy

Cancer, 1986
Intracarotid 1,3-bis(2-chloroethyl)-1-nitrosurea (BCNU) is now a frequently used chemotherapeutic agent for high-grade glial neoplasms. The toxicity from such therapy has not been well-documented. A 50-year-old man with a left frontoparietal grade 4 astrocytoma received three injections of intracarotid BCNU, 400 mg each, over a 2-month period.
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