Results 11 to 20 of about 11,962 (196)
Early-Onset Mucocutaneous Findings and Isolated Progressive Thrombocytopenia in a Child With a DKC1 A353V Variant. [PDF]
ABSTRACT Dyskeratosis congenita (DC) is a rare telomere biology disorder characterized by mucocutaneous abnormalities and progressive bone marrow failure. We report a 10‐year‐old boy with a hemizygous DKC1 c.1058C > T (p.Ala353Val) variant who presented with unusually early mucocutaneous findings, including oral leukoplakia at 2 years of age, followed ...
Kasapoğlu H +4 more
europepmc +2 more sources
Proliferative Verrucous Leukoplakia Revisited: A Retrospective Clinicopathological Study
(1) Objective: To review the criteria proposed by Cerero-Lapiedra et al. and to retrospectively identify the under-diagnosed disease in patients diagnosed with proliferative verrucous leukoplakia.
Snehashish Ghosh +13 more
doaj +1 more source
Context and Aim: Oral leukoplakia has recently been re-defined as “a predominantly white lesion of the oral mucosa that cannot be characterised as any other definable lesion”.
Jobin Mathew Kuthoor +3 more
doaj +1 more source
It is hypothesized that same driver gene mutations should be present in both oral leukoplakia and cancer tissues. So, we attempted to find out mutations at one of the driver genes, CASP8, in cancer and adjacent leukoplakia tissues.
Richa Singh +8 more
doaj +1 more source
Background The tongue has been identified as a high-risk site for malignant transformation of oral leukoplakia. The purpose of this study was to investigate the clinicopathological characteristics and treatment outcomes of the dorsal and ventrolateral ...
Shih-Wei Yang +4 more
doaj +1 more source
Immunohistochemical Evaluation of EGFR Expression in Oral Dysplastic and Non-Dysplastic Leukoplakia [PDF]
Background: This study aimed to evaluate the expression of epidermal growth factor receptor (EGFR) in oral leukoplakia with and without dysplasia and normal mucosa by immunohistochemistry.Materials and Methods: In this study, 45 samples of oral ...
Nasrollah Saghravanian +3 more
doaj +1 more source
Characterisation of Clinicopathological and Molecular Features of Leukoplakia not Associated with Tobacco- A Scoping Review [PDF]
Tobacco has been implicated as the strongest risk factor for oral malignancies and common potentially malignant disorders. Recent trend shows an increase in the prevalence of these lesions in non tobacco population.
Kalpa Pandya +3 more
doaj +1 more source
Oral Leukoplakia as It Relates to HPV Infection: A Review
Leukoplakia is the most common potentially malignant lesion of the oral cavity and can be categorised according to its clinical appearance as homogeneous or nonhomogenous. Tobacco and areca nut use, either alone or in combination are the most common risk
L. Feller, J. Lemmer
doaj +1 more source
Evaluation of CD44 and TGF-B Expression in Oral Carcinogenesis
Statement of the Problem: Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity. Early diagnosis of OSCC by using biomarkers provides preventive treatment approach to suppress the disease in early stages.
Narges Ghazi +3 more
doaj +1 more source
Introduction: Leukoplakia is a precancerous lesion considered to be within the spectrum of histopathological results from parakeratosis, through stages of dysplasia to invasive cancer.
Flaminia Campo MD +5 more
doaj +1 more source

