Results 11 to 20 of about 11,962 (196)

Early-Onset Mucocutaneous Findings and Isolated Progressive Thrombocytopenia in a Child With a DKC1 A353V Variant. [PDF]

open access: yesClin Case Rep
ABSTRACT Dyskeratosis congenita (DC) is a rare telomere biology disorder characterized by mucocutaneous abnormalities and progressive bone marrow failure. We report a 10‐year‐old boy with a hemizygous DKC1 c.1058C > T (p.Ala353Val) variant who presented with unusually early mucocutaneous findings, including oral leukoplakia at 2 years of age, followed ...
Kasapoğlu H   +4 more
europepmc   +2 more sources

Proliferative Verrucous Leukoplakia Revisited: A Retrospective Clinicopathological Study

open access: yesClinics and Practice, 2021
(1) Objective: To review the criteria proposed by Cerero-Lapiedra et al. and to retrospectively identify the under-diagnosed disease in patients diagnosed with proliferative verrucous leukoplakia.
Snehashish Ghosh   +13 more
doaj   +1 more source

A comparative investigation of the activity of superoxide dismutase in patients with leukoplakia and healthy controls

open access: yesIndian Journal of Dental Research, 2022
Context and Aim: Oral leukoplakia has recently been re-defined as “a predominantly white lesion of the oral mucosa that cannot be characterised as any other definable lesion”.
Jobin Mathew Kuthoor   +3 more
doaj   +1 more source

Study of Caspase 8 mutation in oral cancer and adjacent precancer tissues and implication in progression.

open access: yesPLoS ONE, 2020
It is hypothesized that same driver gene mutations should be present in both oral leukoplakia and cancer tissues. So, we attempted to find out mutations at one of the driver genes, CASP8, in cancer and adjacent leukoplakia tissues.
Richa Singh   +8 more
doaj   +1 more source

An anatomical perspective on clinicopathological characteristics and treatment outcomes of dorsal and ventrolateral tongue leukoplakia after carbon dioxide laser surgery

open access: yesBMC Oral Health, 2021
Background The tongue has been identified as a high-risk site for malignant transformation of oral leukoplakia. The purpose of this study was to investigate the clinicopathological characteristics and treatment outcomes of the dorsal and ventrolateral ...
Shih-Wei Yang   +4 more
doaj   +1 more source

Immunohistochemical Evaluation of EGFR Expression in Oral Dysplastic and Non-Dysplastic Leukoplakia [PDF]

open access: yesJournal of Mashhad Dental School, 2023
Background: This study aimed to evaluate the expression of epidermal growth factor receptor (EGFR) in oral leukoplakia with and without dysplasia and normal mucosa by immunohistochemistry.Materials and Methods: In this study, 45 samples of oral ...
Nasrollah Saghravanian   +3 more
doaj   +1 more source

Characterisation of Clinicopathological and Molecular Features of Leukoplakia not Associated with Tobacco- A Scoping Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Tobacco has been implicated as the strongest risk factor for oral malignancies and common potentially malignant disorders. Recent trend shows an increase in the prevalence of these lesions in non tobacco population.
Kalpa Pandya   +3 more
doaj   +1 more source

Oral Leukoplakia as It Relates to HPV Infection: A Review

open access: yesInternational Journal of Dentistry, 2012
Leukoplakia is the most common potentially malignant lesion of the oral cavity and can be categorised according to its clinical appearance as homogeneous or nonhomogenous. Tobacco and areca nut use, either alone or in combination are the most common risk
L. Feller, J. Lemmer
doaj   +1 more source

Evaluation of CD44 and TGF-B Expression in Oral Carcinogenesis

open access: yesJournal of Dentistry, 2021
Statement of the Problem: Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity. Early diagnosis of OSCC by using biomarkers provides preventive treatment approach to suppress the disease in early stages.
Narges Ghazi   +3 more
doaj   +1 more source

Role of Narrow Band Imaging Endoscopy in Preoperative Evaluation of Laryngeal Leukoplakia: A Review of the Literature

open access: yesEar, Nose & Throat Journal, 2022
Introduction: Leukoplakia is a precancerous lesion considered to be within the spectrum of histopathological results from parakeratosis, through stages of dysplasia to invasive cancer.
Flaminia Campo MD   +5 more
doaj   +1 more source

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