Results 31 to 40 of about 11,962 (196)

Nuclear localization of beta-catenin involved in precancerous change in oral leukoplakia

Molecular Cancer, 2007
Background Oral leukoplakia is a precancerous change developed in the oral mucosa, and the mechanism that oral leukoplakia becomes malignant through atypical epithelium is not known.
Hata Tsuyoshi, Deguchi Hiroyo, Wada Naoyuki, Ito Satoshi, Ishida Kosei, Hosoda Masaru, Nohno Tsutomu   +6 more
doaj   +1 more source

Evaluation of salivary Chemerin in oral leukoplakia, oral squamous cell carcinoma and healthy controls

Journal of Orofacial Sciences, 2023
Introduction: Chemerin is a multifunctional chemoattractant cytokine, encoded by RARRES2 gene. Its role in oral carcinogenesis is largely unexplored. Study was undertaken to evaluate the role of salivary chemerin as a potential biomarker in the early ...
Karthika Pradeep Susha, Rathy Ravindran
doaj   +1 more source

Strategies for Identification and Mitigation of Sanguinarine in Mustard Oil Adulterated by Argemone—A Comprehensive Review

Food Chemistry International, EarlyView.
Sanguinarine, a toxic alkaloid present in argemone, can lead to epidemic dropsy or chronic diseases through DNA intercalation and immune system suppression. Regulatory efforts face challenges due to economic motivations for adulteration as well as technical, social, and infrastructure barriers.
Gururaj Pejavara Narayana, Subhangi Panigrahi, Suresh Kumar Kalakandan, Hema Vincent, Ashish Rawson   +4 more
wiley   +1 more source

Current Evidence in Diagnosis and Treatment of Proliferative Verrucous Leukoplakia

Annals of Saudi Medicine, 2012
Proliferative verrucous leukoplakia is multifocal and progressive lesion with a high rate of malignant transformation. This short review highlights the diagnosis, traditional treatment and the current management of the disease.
Mohamed Yasser Kharma, Basal Tarakji
doaj   +1 more source

A comparison of salivary thiocyanate in cigarette smokers with and without oral leukoplakia: A biochemical study

SRM Journal of Research in Dental Sciences, 2020
Objective and Background: Determining SCN (thiocyanate) levels in saliva has been the most frequently used biochemical tests for establishing an incidence of tobacco consumption among smokers and can be used as biochemical indicator in the evaluation of ...
Anshul Aggarwal, Neha Agrawal, Md Asdullah, Rati Goyal   +3 more
doaj   +1 more source

Malignant Transformation of Oral Epithelial Dysplasia in Southern Finland

Head &Neck, EarlyView.
ABSTRACT Background Oral epithelial dysplasia (OED) often precedes oral squamous cell carcinoma (OSCC). The aim was to elucidate the risk and time of malignant transformation (MT) of OED. Methods Patients diagnosed with OED between 2001 and 2011 in Helsinki and Uusimaa, Finland were included.
Katariina Leino, Hanna K. Laine, Ville Kinnula, Jaana Rautava   +3 more
wiley   +1 more source

Expression of CD44 and SALL4 in Leukoplakia and Oral Squamous Cell Carcinoma

Journal of Pharmacy and Bioallied Sciences
CD44 and SALL4 are markers of stemness and expressed in cancer stem cells (CSCs). Their deregulated expression was seen in various tumors and has been correlated with clinical severity.
Sahoo Pravudeva, Panda Abikshyeet, Dash Kailash Chandra, Bhuyian Lipsa, Raghuvanshi Malvika, Panda Baisali   +5 more
doaj   +1 more source

Effect of smoking status and programmed death-ligand 1 expression on the microenvironment and malignant transformation of oral leukoplakia: A retrospective cohort study.

PLoS ONE, 2021
Tobacco smoking is associated with an increased risk of oral leukoplakia and head and neck cancer. Although it has recently been reported that the establishment of an immunosuppressive microenvironment in oral potentially malignant disorders may lead to ...
Takahiro Yagyuu, Naoki Funayama, Mitsuhiko Imada, Tadaaki Kirita   +3 more
doaj   +1 more source

Pattern of Progression of Oral Potentially Malignant Disorders From Real‐World Data: A 24‐Year Study

Head &Neck, EarlyView.
ABSTRACT Background Oral potentially malignant disorder (OPMD) prognostication is limited by uncertainty of which lesions will progress and the aggressiveness of lesion progression. We defined patterns and kinetics of progression in a large cohort of OPMD subjected to serial clinical and histologic examinations. Methods This 24‐year study evaluated the
Subin Surendran, Sumsum P. Sunny, Preethi M. Chathoth, William J. Magner, S. Lynn Sigurdson, Mihai Merzianu, Norbert Sule, Anurag K. Singh, Kimberly E. Wooten, Ryan P. McSpadden, Vishal Gupta, Amritha Suresh, Ashok Z. Samuel, Rohit Bhargava, Praveen N. Birur, Wesley L. Hicks Jr, Moni Abraham Kuriakose   +16 more
wiley   +1 more source

Early detection and treatment of Speckled leukoplakia

Dental Journal, 2016
Background: Leukoplakia is one of potentially malignant disorders that can be found on oral mucosa. Speckled leukoplakia is a rare type of leukoplakia with a very high risk of premalignant growth.
Selviana Tampoma, Iwan Hernawan
doaj   +1 more source