Results 41 to 50 of about 24,304 (227)

A comparison of salivary thiocyanate in cigarette smokers with and without oral leukoplakia: A biochemical study

SRM Journal of Research in Dental Sciences, 2020
Objective and Background: Determining SCN (thiocyanate) levels in saliva has been the most frequently used biochemical tests for establishing an incidence of tobacco consumption among smokers and can be used as biochemical indicator in the evaluation of ...
Anshul Aggarwal, Neha Agrawal, Md Asdullah, Rati Goyal   +3 more
doaj   +1 more source

Diagnostic criteria in proliferative verrucous leukoplakia: evaluation [PDF]

, 2014
Objectives: to evaluate the ability of the diagnostic criteria proposed by Cerero et al in 2010 to perform an early diagnose in patients with proliferative verrucous leukoplakia.
Casado De La Cruz, Laura, Cerero Lapiedra, Rocío, Esparza Gómez, Germán Carlos, García Chías, Begoña   +3 more
core   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Current Evidence in Diagnosis and Treatment of Proliferative Verrucous Leukoplakia

Annals of Saudi Medicine, 2012
Proliferative verrucous leukoplakia is multifocal and progressive lesion with a high rate of malignant transformation. This short review highlights the diagnosis, traditional treatment and the current management of the disease.
Mohamed Yasser Kharma, Basal Tarakji
doaj   +1 more source

Greater Attention to Gingival Cancer and Floor of Mouth Cancer: Based on a Retrospective Analysis of Oral Cancer Across Different Subsites

Head &Neck, EarlyView.
ABSTRACT Background The gingiva and floor of the mouth are distinct subsites, and oral squamous cell carcinoma (OSCC) originating in these locations warrants further indepth understanding. Methods This study enrolled patients with OSCC from 2000 to 2020, and analyzed the clinicopathological characteristics.
Hao Li, Yi Ding, Yansheng Wu, Yan Fang, Xinhua Li, Weifeng Shi, Shaoshi Chen, Ailin Yang, Jin Zhang, Ruoyu Shi, Chao Jing, Xudong Wang, Yuansheng Duan   +12 more
wiley   +1 more source

Expression of CD44 and SALL4 in Leukoplakia and Oral Squamous Cell Carcinoma

Journal of Pharmacy and Bioallied Sciences
CD44 and SALL4 are markers of stemness and expressed in cancer stem cells (CSCs). Their deregulated expression was seen in various tumors and has been correlated with clinical severity.
Sahoo Pravudeva, Panda Abikshyeet, Dash Kailash Chandra, Bhuyian Lipsa, Raghuvanshi Malvika, Panda Baisali   +5 more
doaj   +1 more source

Early detection and treatment of Speckled leukoplakia

Dental Journal, 2016
Background: Leukoplakia is one of potentially malignant disorders that can be found on oral mucosa. Speckled leukoplakia is a rare type of leukoplakia with a very high risk of premalignant growth.
Selviana Tampoma, Iwan Hernawan
doaj   +1 more source

Effect of smoking status and programmed death-ligand 1 expression on the microenvironment and malignant transformation of oral leukoplakia: A retrospective cohort study.

PLoS ONE, 2021
Tobacco smoking is associated with an increased risk of oral leukoplakia and head and neck cancer. Although it has recently been reported that the establishment of an immunosuppressive microenvironment in oral potentially malignant disorders may lead to ...
Takahiro Yagyuu, Naoki Funayama, Mitsuhiko Imada, Tadaaki Kirita   +3 more
doaj   +1 more source

Evaluation of salivary Chemerin in oral leukoplakia, oral squamous cell carcinoma and healthy controls

Journal of Orofacial Sciences, 2023
Introduction: Chemerin is a multifunctional chemoattractant cytokine, encoded by RARRES2 gene. Its role in oral carcinogenesis is largely unexplored. Study was undertaken to evaluate the role of salivary chemerin as a potential biomarker in the early ...
Karthika Pradeep Susha, Rathy Ravindran
doaj   +1 more source

Hairy Leukoplakia [PDF]

, 2017
Oral hairy leukoplakia (OHL) is a disease of the mucosa first described in 1984. This pathology is associated with Epstein-Barr virus (EBV) and occurs mostly in people with HIV infection, both immunocompromised and immunocompetent, and can affect ...
Agarwala, Sanjiv S., Burgess, Jeff, Cade, James E., Lynch, Denis P, Stafford, Gary L, Vinson, Richard P.   +5 more
core   +1 more source