Results 141 to 150 of about 3,055 (179)

Isolation of Pasteurella haemolytica leukotoxin mutants

Infection and Immunity, 1995
Two mutants of Pasteurella haemolytica A1 that do not produce leukotoxin were isolated. Following mutagenesis, colonies were screened with antiserum by a filter assay for absence of the secreted leukotoxin. The two mutants both appeared to produce normal amounts of other antigens, as judged by reactivity with polyclonal serum from an animal with ...
M, Chidambaram, B, Sharma, S F, Petras, C P, Reese, S, Froshauer, G M, Weinstock   +5 more
openaire   +2 more sources

[ARDS and leukotoxin].

Nihon Kyobu Shikkan Gakkai zasshi, 1991
It is well known that pulmonary influx of neutrophils is involved in lung injury in patients with adult respiratory distress syndrome (ARDS). Neutrophils are major contributors to the self-defence mechanism, however, adverse effects of neutrophils have also been recognized. Recently, we found that a highly toxic substance, 9, 10-epoxy-12-octadecenoate (
T, Ozawa, S, Sugiyama, M, Hayakawa, F, Taki   +3 more
openaire   +1 more source

Mannheimia haemolytica leukotoxin

2010
Mannheimia haemolytica is the primary bacterial pathogen of bovine pneumonic pasteurellosis, an economically important disease of cattle worldwide. Leukotoxin (Lkt) produced by M. haemolytica is the major virulence factor of this organism. The cytolytic activity of Lkt is specific for ruminant leukocytes.
openaire   +2 more sources

Biological and biochemical characterization of Fusobacterium necrophorum leukotoxin

American Journal of Veterinary Research, 1994
Summary Biological and biochemical characteristics of the leukotoxin of Fusobacterium necrophorum were determined. Culture supernatant of F necrophorum was toxic to polymorphonuclear neutrophilic, leukocytes from cattle and sheep, but not to those from pigs and rabbits.
Z L, Tan, T G, Nagaraja, M M, Chengappa, J S, Smith   +3 more
openaire   +2 more sources

Binding of Pasteurella haemolytica leukotoxin to bovine leukocytes

Infection and Immunity, 1997
Pasteurella haemolytica is the principal bacterial pathogen in the bovine respiratory disease complex. This organism produces an exotoxin (referred to as leukotoxin) during logarithmic-phase growth that is a potent leukocyte-modulating agent. At low concentrations, it activates neutrophils and mononuclear phagocytes to release inflammatory mediators ...
J F, Brown, F, Leite, C J, Czuprynski
openaire   +2 more sources

Leukotoxins and the Lung

Pulmonary Pharmacology & Therapeutics, 1999
T, Ishizaki, T, Ozawa, N F, Voelkel
openaire   +2 more sources

IL-1 secretion induced by () is mainly caused by the leukotoxin

International Journal of Medical Microbiology, 2008
Casey Chen, Anders Sjöstedt, Anders Johansson   +2 more
exaly  

Cardiovascular effects of leukotoxin (9,10-epoxy-12-octadecenoate) and free fatty acids in dogs

Cardiovascular Research, 1988
Takamichi Ito, Satoru Sugiyama, Tatsuo Satake   +2 more
exaly  

Cellular Characterization of Leukotoxin Diol-Induced Mitochondrial Dysfunction

Archives of Biochemistry and Biophysics, 2001
Joy C Yang, Bruce D. Hammock, Gino A Cortopassi   +2 more
exaly  

Comparative studies on the biology of Actinobacillus actinomycetemcomitans leukotoxin in primates

Oral Microbiology and Immunology, 1987
J Slots, Shigeyo Sakurada, Jørgen Slots
exaly