Results 1 to 10 of about 6,004 (159)

Inflammatory myopathy and severe rhabdomyolysis induced by leuprolide acetate therapy for prostate cancer: a case report [PDF]

open access: yesJournal of Medical Case Reports, 2011
Introduction Leuprolide acetate is a synthetic analog of gonadotropin-releasing hormone used for the treatment of prostate cancer. Its side effects are hot flashes, nausea, and fatigue.
Rohacek Martin   +2 more
doaj   +4 more sources

Overdiagnosis of a typical carcinoid tumor as an adenocarcinoma of the lung: a case report and review of the literature [PDF]

open access: yesWorld Journal of Surgical Oncology, 2012
Background Overdiagnosis of bronchopulmonary carcinoid tumors together with overtreatment can cause serious postoperative consequences for the patient.
Demirci Ilhan   +5 more
doaj   +3 more sources

Determination of Leuprolide–Fatty Acid Conjugate in Rat Plasma Using LC-MS/MS and Its Pharmacokinetics after Subcutaneous Administration in Rats

open access: yesMolecules, 2022
Leuprolide is a synthetic nonapeptide drug (pyroGlu-His-Trp-Ser-Tyr-d-Leu-Leu-Arg-Pro-NHEt) that acts as a gonadotropin-releasing hormone agonist. The continuous administration of therapeutic doses of leuprolide inhibits gonadotropin secretion, which is ...
Gi-Sang Seong   +6 more
doaj   +1 more source

Impact of Androgen Deprivation Therapy on Cardiovascular Outcomes in Prostate Cancer

open access: yesSociété Internationale d’Urologie Journal, 2022
PurposeSubstantial evidence indicates that men with prostate cancer are at an increased risk for cardiovascular disease, and medical and surgical androgen deprivation therapy is associated with further increased cardiovascular risk. There are conflicting
Laurence Klotz   +3 more
doaj   +1 more source

Different expression of NF-kB and endometrial implant width in the administration of red fruit (Pandanus conoideus Lam) and leuprolide

open access: yesMajalah Obstetri dan Ginekologi, 2022
HIGHLIGHTS 1. Endometriosis treatment remains controversial, whether it should be managed with hormonal modulation and/or surgical removal of the lesion. 2.
Raudatul Hikmah   +2 more
doaj   +1 more source

Clinical development of the GnRH agonist leuprolide acetate depot

open access: yesF&S Reports, 2023
Leuprolide acetate is the first GnRH agonist that entered clinical development after the discovery of the native GnRH. Several long-acting depot formulations of leuprolide acetate (ranging from 1-month to 6-month intramuscular injections) have been ...
Kristof Chwalisz, M.D., Ph.D.
doaj   +1 more source

Aвтоимун тироидит по долга употреба на агонист на гонадотропин- ослободувачки хормон како третман за предвремен централен пубертет – приказ на случај [PDF]

open access: yes, 2020
There is a small number of studies that have reported abnormalities in endocrine function after a long-term gonadotropin-releasing hormone agonist (GnRHa) treatment in girls. This treatment is considered as safe and effective by most authors.
Krstevska-Konstantinova, Marina   +3 more
core   +2 more sources

Leuprolide and triptorelin treatment in children with idiopathic central precocious puberty: an efficacy/tolerability comparison study

open access: yesFrontiers in Pediatrics, 2023
IntroductionCentral precocious puberty (CPP) results from premature activation of hypothalamic-pituitary-gonadal axis, with the consequent increase of gonadotropin-releasing hormone (GnRH); GnRH agonists (GnRHa) represent the gold-standard therapy in ...
M. Valenzise   +13 more
doaj   +1 more source

Impact of luteinizing hormone suppression on hematopoietic recovery after intensive chemotherapy in patients with leukemia

open access: yesHaematologica, 2020
Treatment of acute leukemia with intensive chemotherapy leads to an increased risk of myelosuppression. Luteinizing hormone (LH) blockade improves hematopoietic recovery in mice after radiation or chemotherapy, through protection of the hematopoietic ...
Iman Abou Dalle   +11 more
doaj   +1 more source

Leuprolide Acetate Treatment for Ovarian Cysts in Breast Cancer Patients Under Tamoxifen Therapy

open access: yesGynecology Obstetrics & Reproductive Medicine, 2022
OBJECTIVE: The aim of this study is to evaluate the outcomes of gonadotropin-releasing hormone agonist treatment for ovarian cysts, which are developed during tamoxifen use due to breast cancer.
Şafak Yılmaz Baran   +4 more
doaj   +1 more source

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