Results 41 to 50 of about 6,004 (159)

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, EarlyView.
What's New? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Correlation Between Testosterone and PSA Kinetics in Metastatic Prostate Cancer Patients Treated With Diverse Chemical Castrations

American Journal of Men's Health, 2015
To assess total testosterone and prostatic-specific antigen (PSA) kinetics among diverse chemical castrations, advanced-stage prostate cancer patients were randomized into three groups of 20: Group 1, Leuprolide 3.75 mg; Group 2, Leuprolide 7.5 mg; and ...
Leonardo O. Reis MD, MSc, PhD, Fernandes Denardi MD, PhD, Eliney F. Faria MD, PhD, Elcio Dias Silva MD, PhD   +3 more
doaj   +1 more source

Changes in adenomyosis following elagolix vs leuprolide treatment in a patient with pelvic pain and infertility: A case report

Case Reports in Women's Health, 2023
Adenomyosis is a uterine form of endometriosis that poses unique challenges in the management of infertility. Severe pelvic pain and menorrhagia associated with these conditions are commonly managed with intramuscular injections of a gonadotropin ...
Mariam Barseghyan, J. Graham Theisen, Clara Wang, Larisa Gavrilova-Jordan   +3 more
doaj   +1 more source

Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer. [PDF]

, 2019
In preclinical studies, selenite had single agent activity and radiosensitized tumors in vivo. Here we report results from a Phase 1 trial in 15 patients with metastatic cancer treated with selenite (5.5 to 49.5 mg) orally as a single dose 2 hours before
Buyyounouski, Mark K, Grimes, Kevin, Jayachandran, Priya, Keeling, Christine A, Knox, Susan J, Sandhu, Navjot, Savic, Rada, Shura, Lei, Stamps-DeAnda, Stacy Leanne, Stevens, Kathryn J   +9 more
core  

Gonadotrophin-releasing hormone agonist protocols for pituitary suppression in assisted reproduction [PDF]

, 2015
Peer reviewedPublisher ...
Basios, George, Bhattacharya, Siladitya, Gibreel, Ahmed, Maheshwari, Abha, Siristatidis, Charalampos S   +4 more
core   +1 more source

Treatment Response and Outcomes of Prostate Cancer Patients Carrying the Germline MMS22L F722fs Mutation

The Prostate, EarlyView.
ABSTRACT Background Methyl Methanesulfonate‐Sensitivity Protein 22‐Like (MMS22L) plays a key role in homology‐directed DNA repair, and experimental models have shown that its loss confers sensitivity to Poly (ADP‐ribose) polymerase inhibitors (PARPi).
Mayuko Kanayama, Violet A. Daniels, Marta Gielzak, Alex Brame, Misop Han, Li Jia, Jianfeng Xu, Tamara L. Lotan, Mario A. Eisenberger, Catherine H. Marshall, Patrick C. Walsh, William B. Isaacs, Jun Luo   +12 more
wiley   +1 more source

Genomic and Clinical Impact of Smoking on Therapeutic Outcomes in Prostate Cancer: A Public Databases Analysis

The Prostate, EarlyView.
ABSTRACT Background In prostate cancer (PCa), smoking history is associated with more aggressive clinicopathological features, reduced efficacy of androgen deprivation therapy, and poorer overall survival (OS). However, its impact on survival outcomes in patients receiving taxane chemotherapy, poly ADP‐ribose polymerase inhibitor (PARPi), or immune ...
Tomoya Hatayama, Yohei Sekino, Go Kobayashi, Kazuma Yukihiro, Yoshinori Nakano, Shinsaku Tasaka, Naofumi Nomura, Yuki Kohada, Kenshiro Takemoto, Miki Naito, Shunsuke Miyamoto, Kohei Kobatake, Hiroyuki Kitano, Keisuke Goto, Akihiro Goriki, Keisuke Hieda, Nobuyuki Hinata   +16 more
wiley   +1 more source

Cytoreductive Radical Prostatectomy in Oligometastatic Prostate Cancer: Single‐Centre Experience

BJUI Compass, Volume 7, Issue 3, March 2026.
Abstract Objective This study aims to evaluate the oncological outcomes, functional recovery and overall satisfaction following cytoreductive radical prostatectomy (CRP) in patients with oligometastatic prostate cancer treated at a single tertiary‐care centre.
Khawaja Abdul Rouf, Akil Latief, Sajad Ahmad Para, Younis Mushtaq, Shubham Gupta, Sajad Ahmad Malik, Saqib Mehdi, Arif Hamid   +7 more
wiley   +1 more source

Effects of Combined Laparoscopic Cystectomy and Leuprolide Acetate Therapy on Anti-Mullerian Hormone Level and Antral Follicle Count Profile in Endometriosis

Obgynia, 2023
Objective: This study examines the effectiveness of combined laparoscopic cystectomy and leuprolide acetate therapy on AMH level and AFC profile in endometriosis. Method: This study is a randomized controlled clinical trial with open label form.
Fatimah Usman, Bagus Hilmawan, Kemas Yusuf, Heriyadi Manan, Theodorus Theodorus, Hana Andrina   +5 more
doaj   +1 more source

The role of gonadotrophin-releasing hormone antagonists in the treatment of patients with advanced hormone-dependent prostate cancer in the UK. [PDF]

, 2016
PURPOSE: Comparing gonadotrophin-releasing hormone (GnRH) antagonists and agonists as androgen deprivation therapy for advanced prostate cancer (PC). METHODS: This article stems from a round-table meeting in December 2014 to compare the properties of ...
A Nanda, A Plekhanov, A Radu, B Ehdaie, B Tombal, B Tombal, B Tombal, B Tombal, B Turner, B Turner, Bruce Turner, C Huggins, CJ Nelson, CJ Sweeney, D Ilic, Damien Greene, Derek J. Rosario, DM Kelly, ED Crawford, F Tanriverdi, FH Schröder, G-W Lin, GG Schwartz, GJ Bubley, GN Levine, H Chen, H Poppel Van, HC Blair, Heather Payne, HH Chao, HJ Green, James Green, JD Jacobson, JM Wilson, L Boccon-Gibod, L Bourke, L Drudge-coates, L Klotz, L Klotz, M Hanninen, M Hemelrijck Van, M Hussain, MA Perlmutter, MG Oefelein, MHA Hussain, Mike Kirby, N Sharifi, ND Shore, NL Keating, P Libby, P Libby, Patrick Davey, PC Albertsen, S Gilbert, Scandanavian Simvastatin Survival Study Group, WA Satariano   +55 more
core   +2 more sources