Evaluation of hypersensitivity reactions with leuprolide acetate and triptorelin acetate in children [PDF]
Indian Journal of Endocrinology and Metabolism, 2021 Introduction: Gonadotropin releasing hormone analogues (GnRHa) are commonly used to treat central precocious puberty (CPP). Generally, they are well-tolerated; however adverse reactions have been reported.
Azize Pınar Metbulut +4 more
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Inflammatory myopathy and severe rhabdomyolysis induced by leuprolide acetate therapy for prostate cancer: a case report [PDF]
Journal of Medical Case Reports, 2011 Introduction Leuprolide acetate is a synthetic analog of gonadotropin-releasing hormone used for the treatment of prostate cancer. Its side effects are hot flashes, nausea, and fatigue.
Rohacek Martin +2 more
doaj +4 more sources
Clinical development of the GnRH agonist leuprolide acetate depot [PDF]
F&S Reports, 2023 Leuprolide acetate is the first GnRH agonist that entered clinical development after the discovery of the native GnRH. Several long-acting depot formulations of leuprolide acetate (ranging from 1-month to 6-month intramuscular injections) have been ...
Kristof Chwalisz, M.D., Ph.D.
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Case - Leuprolide acetate-induced necrotic skin ulceration. [PDF]
Can Urol Assoc J, 2023 Androgen deprivation therapy (ADT) has become a well-established modality in the management of locally advanced and metastatic prostate cancer.1 Leuprolide acetate, a synthetically derived gonadotropin-releasing hormone receptor (GnRHR) agonist, is commonly used for ADT in men.2 Despite proven effectiveness, the administration of GnRHR agonists is ...
Ian Janes WC, Ogunyemi B, Andrews M.
europepmc +3 more sources
Efficacy of leuprolide acetate versus triptorelin pamoate administered every 3 months for treatment of central precocious puberty [PDF]
Clinical and Experimental PediatricsBackground Central precocious puberty (CPP) is typically treated with gonadotropin-releasing hormone (GnRH) agonists. Although numerous GnRH agonist variants are available, limited research has compared the efficacy of leuprolide acetate and triptorelin ...
Thanaporn Thaneetrakool +5 more
doaj +2 more sources
Treatment of overweight and obese girls experiencing central precocious puberty: a comparison of the effectiveness of leuprolide acetate and triptorelin pamoate [PDF]
Annals of Pediatric Endocrinology & MetabolismPurpose Gonadotropin-releasing hormone agonists are the standard treatment for central precocious puberty (CPP). These agonists include leuprolide acetate and triptorelin pamoate, but research data for the relative effectiveness of these 2 treatments in ...
Thanaporn Thaneetrakool +6 more
doaj +2 more sources
A single-dose, randomized, open-labeled, parallel-group study comparing the pharmacokinetics, pharmacodynamics and safety of leuprolide acetate microspheres 3.75 mg and Enantone® 3.75 mg in healthy male subjects [PDF]
Frontiers in Pharmacology, 2022 Leuprolide acetate microspheres developed by Shanghai Livzon Pharmaceutical Co., Ltd. (T) have been marketed in China for more than 10 years, benefiting a large number of patients, and will continue to play an important role in China.
Xingjiang Hu +8 more
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When leuprolide acetate is essential to care: A review of the literature and framework for assessing drug allergy [PDF]
Journal of Allergy and Clinical Immunology: GlobalGonadotropin-releasing hormone agonists are uncommonly associated with hypersensitivity reactions. To date, there have been few reports of these cases by allergists and no clear published protocols on testing.
Ami P. Belmont, MD +4 more
doaj +2 more sources
Two cases of MACS due to PBMAH associated with an in vivo aberrant response to LHRH treated with leuprolide acetate [PDF]
Endocrinology, Diabetes & Metabolism Case ReportsWe describe two rare cases of primary bilateral macronodular adrenal hyperplasia (PBMAH) with mild autonomous cortisol secretion (MACS), incidentally discovered and further evaluated for aberrant cortisol responses to various stimuli.
Laurie Branchaud-Croisetière +2 more
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Effectiveness of leuprolide acetate administered monthly compared to three-monthly in the treatment of central precocious puberty: evaluation at the end of treatment [PDF]
Frontiers in EndocrinologyIntroductionGonadotropin-releasing hormone (GnRH) analogs are the standard treatment for central precocious puberty (CPP). Although there are numerous varieties of GnRH agonists, the effectiveness of 1-monthly compared with 3-monthly Leuprolide acetate ...
Thanaporn Thaneetrakool +6 more
doaj +2 more sources