Results 171 to 180 of about 7,653 (215)

Histopathological changes in leiomyomata treated with leuprolide acetate

Fertility and Sterility, 1990
Several studies have shown a decrease in uterine and/or leiomyoma volume when treated with leuprolide acetate (LA), a widely used gonadotropin-releasing hormone agonist. The mechanism by which these changes occur is unknown. In this study, the histopathological slides of 31 women of reproductive age who underwent hysterectomy or myomectomy were blindly
N B, Upadhyaya, M C, Doody, P B, Googe
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Leuprolide acetate treatment of adrenocortical disease in ferrets

Journal of the American Veterinary Medical Association, 2001
Abstract Objective—To determine the effects of leuprolide acetate, a long-acting gonadotropin-releasing hormone analog, in ferrets with adrenocortical diseases. Design—Case series. Animals—20 ferrets with adrenocortical disease diagnosed on the basis of clinical signs and plasma sex hormone concentrations ...
R A, Wagner, E M, Bailey, J F, Schneider, J W, Oliver   +3 more
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Characterization of the solution conformations of leuprolide acetate

The Journal of Peptide Research, 2002
Abstract: Leuprolide acetate (pGlu‐His‐Trp‐Ser‐Tyr‐d‐Leu‐Leu‐Arg‐Pro‐NHEt), a potent LHRH agonist in wide clinical use, was characterized conformationally by NMR and circular dichroism. It displayed quite different preferred conformations under different solution conditions: two low population β‐turns in water, a nascent helix in TFE/water at low pH ...
J D, Meyer, M C, Manning, D G, Vander Velde   +2 more
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Leuprolide Acetate and Central Retinal Vein Occlusion

Ophthalmic Surgery, Lasers and Imaging Retina, 2007
<P>A 63-year-old man suffered a central retinal vein occlusion 2 months after he began taking leuprolide acetate for prostate cancer. Despite control for possible systemic hypertension (126/90 mm Hg) and mild hypercholesterolemia (total cholesterol level = 246 mg/dL [range: 16 to 200 mg/dL], high-density lipoprotein level = 67 mg/dL [range: 40 to
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Leuprolide acetate: a drug of diverse clinical applications

Expert Opinion on Investigational Drugs, 2007
Leuprolide acetate is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization techniques. As its basic mechanism of action, leuprolide acetate
Andrea C, Wilson, Sivan Vadakkadath, Meethal, Richard L, Bowen, Craig S, Atwood   +3 more
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Treatment of Pedophilia with Leuprolide Acetate

Journal of Psychology & Human Sexuality, 2002
Abstract To date, the literature on the treatment of individuals who have committed sexual offenses has focused primarily on psychotherapeutic interventions and the use of antiandrogens. Recently case reports and small series supporting the efficacy of other psychiatric medication, such as serotonin reuptake inhibitors, have been published.
Nancy Raymond, Bean Robinson, Chris Kraft, Barry Rittberg, Eli Coleman   +4 more
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Leuprolide Acetate

American Journal of Cancer, 2003
Katherine F. Croom, Caroline M. Perry
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Leuprolide acetate‐stimulated androgen response during female puberty

Clinical Endocrinology, 2015
SummaryBackgroundA physiological increase in androgen levels occurs during adolescence. Measuring androgen concentrations is the best method to distinguish normal evolution processes from hyperandrogenic disorders.HypothesisThe increase in circulating androgens during puberty is inversely associated with insulin sensitivity in normal weight girls ...
Hernández, María Isabel, Martínez Aguayo, Alejandro Gregorio, Cavada, Gabriel, Avila, Alejandra, Iñiguez, German, Mericq, Veronica   +5 more
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Subcutaneous low dose leuprolide acetate depot versus leuprolide acetate for women undergoing ovarian stimulation for in-vitro fertilization

Human Reproduction, 1995
A total of 100 women undergoing ovarian stimulation with gonadotrophin-releasing hormone agonist (GnRHa) and a human menopausal gonadotrophin (HMG) for in-vitro fertilization (IVF) participated in this randomized comparative study. Leuprolide acetate at a dose of 0.5 mg/day s.c.
H D, Tsai, C M, Chen, H Y, Lo, C C, Chang   +3 more
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Leuprolide acetate-induced dermatitis herpetiformis.

Cutis, 2005
Dermatitis herpetiformis (DH) is a chronic, pruritic, papulovesicular dermatosis on extensor surfaces that is characterized by a neutrophilic infiltrate and granular immunoglobulin A deposition at the dermal papillae. Although the presence of immunoglobulin A in the skin and the severity of DH are known to be associated with gluten intake, few drugs ...
Ronald E, Grimwood, Adrian, Guevara
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