Results 11 to 20 of about 7,653 (215)

Electrocardiographic Findings in Children Treated with Leuprolide Acetate for Precocious Puberty: Does it Cause Prolonged QT? [PDF]

JCRPE
INTRODUCTION: Central precocious puberty (CPP) is treated with long-acting gonadotropin releasing hormone (GnRH) analogues (GnRHa). Some adult patients undergoing GnRHa treatment experienced prolonged QT syndrome, which is associated with an increased ...
Esma Ebru Altun, Ayşe Yaşar, Fatma Dursun, Gülcan Seymen, Heves Kırmızıbekmez   +4 more
doaj   +2 more sources

Pharmacokinetic and pharmacodynamic comparison of subcutaneous intramuscular leuprolide acetate formulations in male subjects [PDF]

Therapeutic Advances in Urology, 2018
Background: The aim of this study was to compare the pharmacokinetics (PK) and pharmacodynamics (PD) of two distinct formulations of leuprolide acetate (LA); subcutaneous (SC) injection and intramuscular (IM) injection. Methods: A total of 32 healthy men
Daniel Saltzstein, Neal D. Shore, Judd W. Moul, Franklin Chu, Raoul Concepcion, Stephan de la Motte, John A. McLane, Stuart Atkinson, Alex Yang, E. David Crawford   +9 more
doaj   +2 more sources

Ulipristal Acetate versus Leuprolide Acetate for Uterine Fibroids [PDF]

New England Journal of Medicine, 2012
The efficacy and side-effect profile of ulipristal acetate as compared with those of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are unclear.In this double-blind noninferiority trial, we randomly assigned 307 patients with symptomatic fibroids and excessive uterine bleeding to receive 3 months of daily therapy ...
Donnez J1, Tomaszewski J, Vázquez F, Bouchard P, Lemieszczuk B, Baró F, Nouri K, Selvaggi L, Sodowski K, Bestel E, Terrill P, Osterloh I, Loumaye E, THE PEARL II Study Group, MELIS, GIAN BENEDETTO   +14 more
  +6 more sources

Leuprolide Acetate Treatment for Ovarian Cysts in Breast Cancer Patients Under Tamoxifen Therapy

Gynecology Obstetrics & Reproductive Medicine, 2022
OBJECTIVE: The aim of this study is to evaluate the outcomes of gonadotropin-releasing hormone agonist treatment for ovarian cysts, which are developed during tamoxifen use due to breast cancer.
Şafak Yılmaz Baran, Gulsen Dogan Durdag, Songul Alemdaroglu, Sirin Aydin, Husnu Celik   +4 more
doaj   +1 more source

Changes in adenomyosis following elagolix vs leuprolide treatment in a patient with pelvic pain and infertility: A case report

Case Reports in Women's Health, 2023
Adenomyosis is a uterine form of endometriosis that poses unique challenges in the management of infertility. Severe pelvic pain and menorrhagia associated with these conditions are commonly managed with intramuscular injections of a gonadotropin ...
Mariam Barseghyan, J. Graham Theisen, Clara Wang, Larisa Gavrilova-Jordan   +3 more
doaj   +1 more source

Efficacy of Leuprorelide acetate (Eligard®) in daily practice in Brazil: a retrospective study with depot formulations in patients with prostate cancer [PDF]

International Brazilian Journal of Urology, 2020
Introduction: Androgen deprivation therapy (ADT) is the mainstay of therapy for advanced prostate cancer. Studies addressing the efficacy of different depot formulations of long acting luteinizing hormone releasing hormone agonists in the Brazilian ...
Carla S. M. de Freitas, Aleida N. Soares
doaj   +1 more source

Effects of Combined Laparoscopic Cystectomy and Leuprolide Acetate Therapy on Anti-Mullerian Hormone Level and Antral Follicle Count Profile in Endometriosis

Obgynia, 2023
Objective: This study examines the effectiveness of combined laparoscopic cystectomy and leuprolide acetate therapy on AMH level and AFC profile in endometriosis. Method: This study is a randomized controlled clinical trial with open label form.
Fatimah Usman, Bagus Hilmawan, Kemas Yusuf, Heriyadi Manan, Theodorus Theodorus, Hana Andrina   +5 more
doaj   +1 more source

Aвтоимун тироидит по долга употреба на агонист на гонадотропин- ослободувачки хормон како третман за предвремен централен пубертет – приказ на случај [PDF]

, 2020
There is a small number of studies that have reported abnormalities in endocrine function after a long-term gonadotropin-releasing hormone agonist (GnRHa) treatment in girls. This treatment is considered as safe and effective by most authors.
Krstevska-Konstantinova, Marina, Kuzevska-Maneva, Konstandina, Murtezani, Avdi, Tankoska, Maja   +3 more
core   +2 more sources

Considerations for Menstrual Suppression in Patients With Hematologic Malignancies. [PDF]

Pharmacotherapy
ABSTRACT Patients who menstruate during treatment for hematologic malignancies have a higher risk of heavy vaginal bleeding due to thrombocytopenia caused by malignancy and myelosuppressive chemotherapy. Heavy menstrual bleeding is associated with significant morbidity in this patient population, and menstrual suppression is a standard of supportive ...
Veeravalli S, Schepers A, Benitez LL, Fraga MS.   +3 more
europepmc   +2 more sources

Fabrication and Release Kinetics of Liposomes Containing Leuprolide Acetate

Journal of Basic and Applied Research in Biomedicine, 2022
The present work is focused on the preparation and in vitro release kinetics of liposomal formulation of Leuprolide Acetate. In this work, “Thin Lipid Film Hydration Method” was used for preparation of Leuprolide Acetate loaded liposomes.
Sudipta Das, Arnab Samanta, Koushik Bankura, Debatri Roy, Amit Nayak   +4 more
doaj   +2 more sources