Results 21 to 30 of about 7,653 (215)

Chronic periadolescent leuprolide exposure affects the development of reproductive physiology and behavior of female and male rats differently, but both mature after treatment termination

Biology of Sex Differences, 2023
Highlights Leuprolide acetate (50 µg/kg, postnatal day 25–50) suppresses pubertal development in female and male rats. Estrous cyclicity is suppressed during treatment in female rats.
Fay A. Guarraci, Layla Avendano, Megan Kelly, Cleriza Estoesta, Bernard Sencherey, Hannah S. Valdivia, Amanda Gale, Lily Yepez, Jasmine B. Belfield, Kristen M. Carter, Natalie Williams, Andrea C. Gore   +11 more
doaj   +1 more source

Leuprolide acetate induces structural and functional recovery of injured spinal cord in rats

Neural Regeneration Research, 2015
Gonadotropin-releasing hormone (GnRH) and its synthetic analog leuprolide acetate, a GnRH agonist, have neurotrophic properties. This study was designed to determine whether administration of leuprolide acetate can improve locomotor behavior, gait ...
Carmen Díaz-Galindo, Beatriz Gómez-González, Eva Salinas, Denisse Calderón-Vallejo, Irma Hernández-Jasso, Eduardo Bautista, J Luis Quintanar   +6 more
doaj   +1 more source

Acute manic and psychotic symptoms following subcutaneous leuprolide acetate in a male patient without prior psychiatric history: A case report and literature review

Urological Science, 2014
Leuprolide acetate is usually used in the treatment of advanced prostate cancer. The adverse events associated with administration of leuprolide acetate include fatigue, hot flashes, loss of libido, impotence, and depression.
Yuan-Hung Pong, Yu-Chuan Lu, Vinscent F.S. Tsai, Pei-Lin Huang, Ju-Ton Hsieh, Hong-Chiang Chang   +5 more
doaj   +1 more source

Effectiveness, Safety and Obedience of Dienogest and Leuprolide Acetate in Postlaparoscopic Endometriosis Patients

Indonesian Journal of Obstetrics and Gynecology, 2020
Objective: Comparing therapeutic effectiveness, safety profile, and adherence between Dienogest and postoperative Leuprolide Acetate in women with endometriosis who underwent laparoscopy.
Joko P. Purwanto, Yusuf Effendi, Heriyadi Manan, Theodorus   +3 more
doaj   +1 more source

A meta-analysis and systematic review of randomized controlled trials with degarelix versus gonadotropin-releasing hormone agonists for advanced prostate cancer [PDF]

, 2016
Our aim was to systematically evaluate the benefits of degarelix as antagonist versus agonists of gonadotropin-releasing hormones (GnRH) for the treatment of advanced prostate cancer (PC).
CATTARINO, SUSANNA, CIARDI, Antonio, Fasulo, Andrea, GENTILE, Vincenzo, GENTILUCCI, ALESSANDRO, INNOCENZI, MICHELE, Maggi, Martina, PETRANGELI, Elisa, PIERELLA, FEDERICO, SALCICCIA, STEFANO, SCIARRA, Alessandro   +10 more
core   +1 more source

Nanochanneled Device and Related Methods [PDF]

, 2013
A nanochannel delivery device and method of manufacturing and use. The nanochannel delivery device comprises an inlet, an outlet, and a nanochannel. The nanochannel may be oriented parallel to the primary plane of the nanochannel delivery device.
Ferrari, Mauro, Fine, Daniel, Goodall, Randy, Grattoni, Alessandro, Hosali, Sharath, Hudson, Lee, Liu, Xuewu, Medema, Ryan   +7 more
core   +5 more sources

Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017 [PDF]

, 2017
The most common endocrinopathy associated with McCune-Albright Syndrome (MAS) is peripheral precocious puberty (PP) which occurs far more often in girls than in boys.
Eugster, Erica A., Neyman, Anna
core   +1 more source

Medical Therapies for Uterine Fibroids - A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials [PDF]

, 2016
BACKGROUND: Uterine fibroids are common, often symptomatic and a third of women need repeated time off work. Consequently 25% to 50% of women with fibroids receive surgical treatment, namely myomectomy or hysterectomy.
A Armstrong, A Daniels, A Golan, A Lethaby, A Lieto, A Zimmermann, AJ Audebert, AJ Friedman, AJ Friedman, AJ Friedman, AJ Friedman, Andrew Horne, AR Williams, AR Williams, B Kroon, BJ Borah, CC Coddington, D De Aloysio, D Mavrelos, D Moher, DD Baird, DD Baird, E Roshdy, E Verspyck, E Zullo, ED Levens, EE Marsh, EK Arleo, EP Morris, ERC, A.D. Cardozo, F Parazzini, F Polatti, F Zullo, F Zullo, G Levy, G Orsini, G Salanti, GH Guyatt, GH Sayed, GS Carls, H Song, HH Bustos Lopez, Ian S. Fraser, J Balasch, J Donnez, J Donnez, J Donnez, J Gerris, J Higgins, J van de Ven, J van de Ven, J Wilkens, JB Engel, Jessica Vaughan, JH Segars, JL Esteve, JL Rutgers, K Chwalisz, K Fiscella, K Puri, KR Hodges, Kurinchi S. Gurusamy, L Deng, L Fedele, L Fedele, L Fedele, L Muzii, Lawrence M. J. Best, LJ Green, LK Nieman, M Bagaria, M De Falco, M Egger, M Engman, M Moshesh, M Rees, M Sayyah-Melli, M Tristan, MA Lumsden, ME Fernandez-Mentoli, ME Parsanezhad, MG Munro, MS Melli, N Biglia, N Johnson, N Varun, O Gregoriou, O Muneyyirci-Delale, O Sadan, P Vercellini, PG Moorman, R D'Anna, R Hudecek, R Seracchioli, RC Reinsch, RL Barbieri, RW Shaw, S Campo, S Constantini, S Jirecek, S Jo Varghese, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, SE Bulun, SL Myers, SS Lim, T Simsek, TG Stovall, TG Stovall, TG Stovall, Toby Richards, WD Schlaff, YB Baytur   +119 more
core   +4 more sources

Effect of goserelin and leuprolide added to the semen on reproductive performance in rabbits — Short communication [PDF]

, 2016
The aim of this study was to evaluate the ability of two synthetic GnRH analogues, goserelin and leuprolide, to induce ovulation in rabbit does using intravaginal administration.
Gogol, Piotr
core   +1 more source

A 6-month depot formulation of leuprolide acetate is safe and effective in daily clinical practice: a non-interventional prospective study in 1273 patients

BMC Urology, 2011
Background Testosterone stimulates growth in many prostate tumours. The established GnRH analogue leuprolide acetate is incorporated in a novel biodegradable polymer matrix (Atrigel® delivery system), that can be administered to reduce testosterone ...
Tunn Ulf W
doaj   +1 more source