Atualização em etiologia, diagnóstico e manejo da precocidade sexual [PDF]
Precocious puberty is defined as the development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. Gonadotropin-dependent precocious puberty (GDPP) results from the premature activation of the hypothalamic ...
ARNHOLD, Ivo J. P. +3 more
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Background: The pathogenesis of endometriosis remains unclear, and involves multifactorial etiologies. The increase in oxidative stress is known to be associated with this disease. Oxidative stress increases angiogenesis and supports the proliferation of
Yuli Trisetiyono +3 more
doaj +1 more source
Practical differences between luteinizing hormone-releasing hormone agonists in prostate cancer: perspectives across the spectrum of care [PDF]
Background:Androgen deprivation therapy (ADT) with luteinizing hormone-releasing hormone (LHRH) agonists is well established for the treatment of men with metastatic prostate cancer.
Janknegt, Robert +5 more
core +1 more source
Central Precocious Puberty: Update on Diagnosis and Treatment [PDF]
Central precocious puberty (CPP) is characterized by the same biochemical and physical features as normally timed puberty but occurs at an abnormally early age. Most cases of CPP are seen in girls, in whom it is usually idiopathic.
Chen, Melinda, Eugster, Erica A.
core +1 more source
Novasure as a mechanical endometrial preparation agent in large uteri. [PDF]
OBJECTIVE: We evaluated Novasure ablation as a mechanical endometrial preparation agent before Roller Ball endometrial ablation in lieu of GnRH agonists in large uteri.
Chatwani, Ashwin J +4 more
core +1 more source
Multicenter clinical trial of leuprolide acetate depot (Luphere depot 3.75 mg) for efficacy and safety in girls with central precocious puberty [PDF]
PurposeWe evaluated the efficacy, safety and psychological aspect of monthly administrations of the gonadotropin-releasing hormone agonists (GnRHa), leuprolide acetate depot (Luphere depot 3.75 mg), in patients with precocious puberty.MethodsA total of ...
You Jin Kim +8 more
doaj +1 more source
Long-Term Results in Girls with Central Precocious Puberty After Leuprolide Acetate Treatment
Aim: Central precocious puberty (CPP) is the development of secondary sex characteristics before the age of 8 years in girls and 9 years in boys due to premature activation of the hypothalamic–pituitary–gonadal (HPG) axis.
Esra BEŞER ÖZMEN, Sibel TULGAR KINIK
doaj +1 more source
Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach. [PDF]
Endometriosis is a complex, estrogen‐dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, have significant side effects (weight gain, mood changes, decreased bone mineral density, and menopausal symptoms) and ...
Rai SK, Kumar R, Khan MI, Kumar A.
europepmc +2 more sources
Gonadotrophin-releasing hormone agonist protocols for pituitary suppression in assisted reproduction [PDF]
Peer reviewedPublisher ...
Basios, George +4 more
core +1 more source
From Endometriosis to Encapsulation: A Case Report of Endometriosis Causing Sclerosing Encapsulating Peritonitis. [PDF]
Sclerosing encapsulating peritonitis is a rare complication of endometriosis that has sparsely been described in the literature. It involves the development of a thick gray‐white fibrotic membrane, which partially or completely encases the small bowel and can spread intraperitoneally to involve surrounding organs, leading to significant morbidity and ...
Frankel L +4 more
europepmc +2 more sources

