Results 41 to 50 of about 7,653 (215)

Health considerations for transgender women and remaining unknowns : a narrative review [PDF]

, 2019
Transgender (trans) women (TW) were assigned male at birth but have a female gender identity or gender expression. The literature on management and health outcomes of TW has grown recently with more publication of research.
Defreyne, Justine, Iwamoto, Sean J, Motmans, Joz, Rothman, Micol S, T'Sjoen, Guy, Van de Bruaene, Laurens, Van Schuylenbergh, Judith   +6 more
core   +1 more source

Luteinizing hormone (LH)-responsive Cushing's syndrome: the demonstration of LH receptor messenger ribonucleic acid in hyperplastic adrenal cells, which respond to chorionic gonadotropin and serotonin agonists in vitro [PDF]

, 2003
In a substantial part of adrenal adenomas and hyperplasias from patients with Cushing's syndrome, cortisol production is controlled by the expression of aberrant hormone receptors on adrenocortical cells.
Bonjer, H.J. (Jaap), Clark, A.J. (Adrian), Feelders, R.A. (Richard), Herder, W.W. (Wouter) de, Hofland, L.J. (Leo), Jong, F.H. (Frank) de, Koetsveld, P.M. (Peter) van, Lamberts, S.W.J. (Steven), Lely, A-J. (Aart-Jan) van der, Themmen, A.P.N. (Axel), Verhoef-Post, M. (Miriam)   +10 more
core   +4 more sources

Successful in vitro fertilization following conservative surgery for synchronous endometrioid tumor of ovary and uterus

Journal of Ovarian Research, 2023
Background Successful pregnancy outcome in women with synchronous ovarian and endometrial cancers is very rare. We report successful pregnancy outcome in a young woman managed conservatively for synchronous endometrial and ovarian cancer.
Vanita Suri, Ramandeep Bansal, Neelam Aggarwal, Pooja Sikka, Seema Chopra, Subhash Chandra Saha, Nalini Gupta, Bhavana Rai   +7 more
doaj   +1 more source

Evaluating the Efficacy of Treatment with a GnRH Analogue in Patients with Central Precocious Puberty

International Journal of Endocrinology, 2015
Objective. GnRH analogues (GnRHa) are used in the treatment of central precocious puberty (CPP). The purpose of this study was to evaluate the efficacy of treatment with a GnRHa (leuprolide acetate) in patients with CPP. Subjects and Methods.
H. Nur Peltek Kendirci, Sebahat Yılmaz Ağladıoğlu, Veysel N. Baş, Aşan Önder, Semra Çetinkaya, Zehra Aycan   +5 more
doaj   +1 more source

Estropause, Sex Hormones and Metal Homeostasis in the Mouse Brain

Frontiers in Neurology, 2022
Alterations in brain metal ion homeostasis have been reported with aging and are implicated in the pathogenesis of neurodegenerative diseases. To assess whether age-related changes in hypothalamic-pituitary-gonadal (HPG) hormones might be involved in ...
Tianbing Liu, Tianbing Liu, Richard L. Bowen, Andrea C. Wilson, Andrea C. Wilson, Craig S. Atwood, Craig S. Atwood, Craig S. Atwood, Craig S. Atwood   +8 more
doaj   +1 more source

A Novel Peptide, HS1002, Enhances Antitumor Activity via Dual Targeting of the GnRH Receptor and Human Telomerase Reverse Transcriptase in Prostate Cancer Cells

MedComm, Volume 7, Issue 3, March 2026.
HS1002, a new peptide targeting GnRHR and hTERT, demonstrates significant Anticancer activity in prostate cancer cells. The mechanism of HS1002 can be attributed to the reduction of serum testosterone levels by desensitization of GnRHR, the downregulation of hTERT expression and telomerase activity, and the enhancement of Anticancer immunity.
Jae Hyeon Park, Joo Chan Lee, Swati Sharma, Chunxue Jiang, Haeun Lee, Hyun‐Ju Park, Hyung Sik Kim   +6 more
wiley   +1 more source

Comparison of gonadotropin releasing hormone agonists (GNRHA) vs aromatase inhibitors on volume of uterine leiomyomas in premenopausal women

Journal of Contemporary Pharmacy, 2023
Among the most prevalent yet poorly understood female health issues is uterine leiomyomas. In order to preserve fertility and avoid or delay surgical intervention, medical treatments are typically considered first-line.
Uzma Hussain, Netasha Nazar, Muhammad Essa, Uswah Shoiab, Maria Imran, Fatima Waheed, Huma Khan   +6 more
doaj  

Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer. [PDF]

, 2019
In preclinical studies, selenite had single agent activity and radiosensitized tumors in vivo. Here we report results from a Phase 1 trial in 15 patients with metastatic cancer treated with selenite (5.5 to 49.5 mg) orally as a single dose 2 hours before
Buyyounouski, Mark K, Grimes, Kevin, Jayachandran, Priya, Keeling, Christine A, Knox, Susan J, Sandhu, Navjot, Savic, Rada, Shura, Lei, Stamps-DeAnda, Stacy Leanne, Stevens, Kathryn J   +9 more
core  

Central precocious puberty: From genetics to treatment [PDF]

, 2018
Central precocious puberty (CPP) results from early activation of the hypothalamic - pituitary -gonadal (HPG) axis and follows the same sequence as normal puberty.
Eugster, Erica A., Schneider Aguirre, Rebecca   +1 more
core   +1 more source

A Reliable Voltammetric Method Utilizing the Effect of an Anionic Surfactant for the Determination of Leuprolide

Acta Chimica Slovenica
Leuprolide acetate is a synthetic gonadotropin-releasing hormone agonist used in the treatment of central precocious puberty, uterine fibroids, endometriosis, and prostate cancer. In this study, the rapid, simple, environmentally friendly, and sensitive
Begüm Evranos Aksöz, Burcu Dogan-Topal
doaj   +1 more source